# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4041722 | ADME | Displacement of [3H]prazosin from recombinant human alpha-1b adrenergic receptor expressed in CHO cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 9 | ALA4041469 | cell-based format | Scientific Literature | |
2. | ALA4041723 | ADME | Displacement of [3H]prazosin from recombinant human alpha-1a adrenergic receptor expressed in CHO cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 9 | ALA4041469 | cell-based format | Scientific Literature | |
3. | ALA4041724 | ADME | Displacement of [3H]prazosin from recombinant human alpha-1d adrenergic receptor expressed in CHO cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 10 | ALA4041469 | cell-based format | Scientific Literature | |
4. | ALA4041725 | Binding | Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor expressed in human HeLa cell membranes after 30 mins by liquid scintillation counting method | Homo sapiens | 32 | ALA4041469 | cell-based format | Scientific Literature | |
5. | ALA4041726 | Functional | Agonist activity at recombinant human 5HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 mins followed by [35S]GTPgammaS addition measured after 30 mins by liquid scintillation counting method | Homo sapiens | 19 | ALA4041469 | cell-based format | Scientific Literature | |
6. | ALA4041727 | Functional | Agonist activity at recombinant human 5HT1A receptor expressed in human HeLa cell membranes assessed as stimulation of [35S]GTPgammaS binding up to 10 uM preincubated for 20 mins followed by [35S]GTPgammaS addition measured after 30 mins by liquid scintillation counting method relative to 5-HT | Homo sapiens | 19 | ALA4041469 | cell-based format | Scientific Literature | |
7. | ALA4041730 | Unassigned | Selectivity index, ratio of Ki for recombinant human alpha-1d adrenergic receptor expressed in CHO cell membranes to Ki for recombinant human 5HT1A receptor expressed in human HeLa cell membranes | Homo sapiens | 4 | ALA4041469 | cell-based format | Scientific Literature | |
8. | ALA4041731 | ADME | Displacement of [3H]N-methylspiperone from recombinant human D2 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting method | Homo sapiens | 3 | ALA4041469 | cell-based format | Scientific Literature | |
9. | ALA4041732 | ADME | Displacement of [3H]N-methylspiperone from recombinant human D3 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting method | Homo sapiens | 3 | ALA4041469 | cell-based format | Scientific Literature | |
10. | ALA4041733 | ADME | Displacement of [3H]N-methylspiperone from recombinant human D4 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting method | Homo sapiens | 3 | ALA4041469 | cell-based format | Scientific Literature | |
11. | ALA4041734 | Unassigned | Selectivity index, ratio of Ki for recombinant human D2 receptor expressed in HEK293 cell membranes to Ki for recombinant human 5HT1A receptor expressed in human HeLa cell membranes | Homo sapiens | 3 | ALA4041469 | cell-based format | Scientific Literature | |
12. | ALA4041735 | Unassigned | Selectivity index, ratio of Ki for recombinant human D3 receptor expressed in HEK293 cell membranes to Ki for recombinant human 5HT1A receptor expressed in human HeLa cell membranes | Homo sapiens | 3 | ALA4041469 | cell-based format | Scientific Literature | |
13. | ALA4041736 | Unassigned | Selectivity index, ratio of Ki for recombinant human D4 receptor expressed in HEK293 cell membranes to Ki for recombinant human 5HT1A receptor expressed in human HeLa cell membranes | Homo sapiens | 3 | ALA4041469 | cell-based format | Scientific Literature |