# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4043569 | A | Half life in human liver microsomes at 3 uM up to 45 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 17 | ALA4043075 | assay format | Scientific Literature | |
2. | ALA4043570 | A | Half life in Sprague-Dawley rat liver microsomes at 3 uM up to 45 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 17 | ALA4043075 | assay format | Scientific Literature | |
3. | ALA4043572 | B | Inhibition of Wistar rat heart mitochondrial CPT-1 assessed as reduction in conversion of palmitoyl CoA and L-carnitine into palmitoylcarnitine preincubated for 3 mins followed by L-carnitine and palmitoyl CoA addition measured for 3.5 mins by spectrophotometric analysis | Rattus norvegicus | 11 | ALA4043075 | single protein format | Scientific Literature | |
4. | ALA4303805 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
5. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
6. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 |