| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4047361 | F | Antiproliferative activity against human KG1 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA4047362 | B | Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assay | Homo sapiens | 34 | single protein format | Scientific Literature | ||
| 3. | ALA4047363 | B | Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assay | Homo sapiens | 33 | single protein format | Scientific Literature | ||
| 4. | ALA4047365 | B | Inhibition of PIM1 in human KG1 cells assessed as reduction in BAD phosphorylation | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA4047366 | A | Permeability from apical to basolateral side in human Caco2/TC7 cells at 5 uM | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA4047367 | B | Inhibition of human ERG by patch clamp assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 7. | ALA4047368 | A | Clearance in human liver microsomes assessed as compound extraction at 5 uM | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 8. | ALA4047369 | P | Thermodynamic solubility of the compound at pH 7.4 | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA4047370 | A | Inhibition of CYP450 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA4047371 | A | Induction of CYP450 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA4047372 | A | AUC (0 to infinity) in mouse at 10 mg/kg, po administered as single dose | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA4047373 | A | Half life in mouse at 3 mg/kg, iv administered as single dose | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA4047374 | A | Half life in mouse at 10 mg/kg, po administered as single dose | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA4047375 | A | Oral bioavailability in mouse at 10 mg/kg administered as single dose | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 15. | ALA4047376 | A | Clearance in mouse at 3 mg/kg, iv administered as single dose | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA4047377 | A | Volume of distribution at steady state in mouse at 3 mg/kg, iv administered as single dose | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA4047378 | A | Cmax in mouse at 3 mg/kg, iv or 10 mg/kg, po administered as single dose | Mus musculus | 3 | organism-based format | Scientific Literature |
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