# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3993207 | B | Positive allosteric modulation of human glycine alpha3beta receptor expressed in HEK293T cells assessed as compound concentration required to induce up to 3-fold leftward shift in glycine-induced increase in chloride ion flux after 4 mins by Schild plot analysis | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
2. | ALA3993208 | A | Intrinsic clearance in mouse liver microsomes up to 40 mins in presence of NADPH | Mus musculus | 23 | assay format | Scientific Literature | ||
3. | ALA3993209 | A | Passive apparent permeability in MDCK cells | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
4. | ALA3993210 | A | Efflux ratio of passive apparent permeability in MDCK cells harboring human MDR1 | Canis lupus familiaris | 15 | cell-based format | Scientific Literature | ||
5. | ALA3993211 | A | Efflux ratio of passive apparent permeability in MDCK cells harboring human BCRP | Canis lupus familiaris | 14 | cell-based format | Scientific Literature | ||
6. | ALA3993222 | U | Ratio of unbound Cmax in mouse brain to EC50 for glycine alpha3 receptor in mouse model of spared nerve injury-induced tactile allodynia at 60 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature |