# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4037498 | Functional | Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 51 | ALA4033785 | cell-based format | Scientific Literature | |
2. | ALA4037499 | Functional | Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 49 | ALA4033785 | cell-based format | Scientific Literature | |
3. | ALA4037500 | Functional | Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 33 | ALA4033785 | cell-based format | Scientific Literature | |
4. | ALA4037501 | Functional | Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 29 | ALA4033785 | cell-based format | Scientific Literature | |
5. | ALA4037503 | Binding | Selectivity ratio of EC50 for mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation to EC50 for mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium accumulation | Homo sapiens | 48 | ALA4033785 | cell-based format | Scientific Literature |