| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4049701 | Binding | Inhibition of recombinant human MMP2 catalytic domain (Tyr110 to Asp452 residues) expressed in yeast using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH as substrate preincubated for 30 mins followed by substrate addition measured every minute for 20 mins by fluorescence assay | Homo sapiens | 6 | ALA4049386 | assay format | Scientific Literature | |
| 2. | ALA4049704 | Binding | Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated for 1 hr followed by substrate addition measured after 80 mins by fluorescence polarization assay | Homo sapiens | 50 | ALA4049386 | cell-based format | Scientific Literature | |
| 3. | ALA4049705 | Functional | Antiproliferative activity against human HCT116 cells after 72 hrs by Cell Titer-Glo assay | Homo sapiens | 11 | ALA4049386 | cell-based format | Scientific Literature | |
| 4. | ALA4049706 | Binding | Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assay | Homo sapiens | 33 | ALA4049386 | single protein format | Scientific Literature | |
| 5. | ALA4049707 | Binding | Inhibition of full length recombinant human C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus expression system using substrate 3 preincubated for 5 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 6 | ALA4049386 | assay format | Scientific Literature | |
| 6. | ALA4049708 | Binding | Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus expression system using substrate 3 preincubated for 5 mins followed by substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 6 | ALA4049386 | assay format | Scientific Literature | |
| 7. | ALA4049709 | Binding | Inhibition of recombinant human 5-LO expressed in baculovirus infected sf9 cells using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured every minute for 20 mins by H2DCFDA dye based fluorescence assay | Homo sapiens | 6 | ALA4049386 | cell-based format | Scientific Literature | |
| 8. | ALA4049710 | Binding | Inhibition of human carbonic anhydrase-2 using p-nitrophenylacetate as substrate preincubated for 10 mins followed by substrate addition | Homo sapiens | 6 | ALA4049386 | single protein format | Scientific Literature |
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