| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4008766 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 20 mins measured after 1 hr by TR-FRET assay | Homo sapiens | 59 | assay format | Scientific Literature | ||
| 2. | ALA4008772 | B | Inhibition of KDM1B (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 3. | ALA4008773 | B | Inhibition of recombinant human MAOA incubated for 15 mins measured after 30 mins by luminescence-Glo assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 4. | ALA4008774 | B | Inhibition of recombinant human MAOB incubated for 15 mins measured after 30 mins by luminescence-Glo assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 5. | ALA4008778 | B | Inhibition of KDM1A in human THP1 cells assessed as increase in CD14 mRNA expression level at 1 uM after 24 hrs by qRT-PCR analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4008780 | B | Inhibition of KDM1A in human THP1 cells assessed as increase in CD11b mRNA expression level at 1 uM after 24 hrs by qRT-PCR analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4008782 | F | Induction of apoptosis in human THP1 cells at 1 uM after 72 hrs by Annexin V-propidium iodide staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4008784 | F | Induction of cell death in human THP1 cells at 1 uM after 72 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4008786 | F | Anticlonogenic activity against human THP1 cells assessed as inhibition of colony formation at 5 uM after 13 days relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4008788 | B | Inhibition of KDM1A in human THP1 cells assessed as increase in CD86 mRNA expression level at 5 uM after 24 hrs by qRT-PCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4008790 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as substrate incubated for 20 mins measured after 1 hr by TR-FRET assay | Homo sapiens | 53 | assay format | Scientific Literature |
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