#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4013437	A	Drug metabolism in human HuH7 cells assessed as carboxylesterase-mediated (S)-isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryloxy)propanoate metabolite formation at 50 uM after 48 hrs by LC/MS/MS analysis	Homo sapiens	1		cell-based format	Scientific Literature
2.	ALA4013438	T	Subacute toxicity in ICR mouse assessed as effect on tubules at 100 to 1000 mg/kg, administered once a day via oral gavage for 14 days by hematoxylin/eosin-staining based microscopic analysis	Mus musculus	1		organism-based format	Scientific Literature
3.	ALA4013439	T	Subacute toxicity in ICR mouse assessed as effect on glomerulus at 100 to 1000 mg/kg, administered once a day via oral gavage for 14 days by hematoxylin/eosin-staining based microscopic analysis	Mus musculus	1		organism-based format	Scientific Literature
4.	ALA4013440	T	Subacute toxicity in ICR mouse assessed as effect on renal architecture at 100 to 1000 mg/kg, administered once a day via oral gavage for 14 days by hematoxylin/eosin-staining based microscopic analysis	Mus musculus	1		organism-based format	Scientific Literature
5.	ALA4013441	T	Subacute toxicity in ICR mouse assessed as effect on hepatic perilobular vein at 100 to 1000 mg/kg, administered once a day via oral gavage for 14 days by hematoxylin/eosin-staining based microscopic analysis	Mus musculus	1		organism-based format	Scientific Literature
6.	ALA4013442	T	Subacute toxicity in ICR mouse assessed as effect on appearance of hepatocytes at 100 to 1000 mg/kg, administered once a day via oral gavage for 14 days by hematoxylin/eosin-staining based microscopic analysis	Mus musculus	1		organism-based format	Scientific Literature
7.	ALA4013443	T	Subacute toxicity in ICR mouse assessed as alteration in basic levels of SGPT at 100 to 1000 mg/kg, administered once a day via oral gavage for 14 days	Mus musculus	1		organism-based format	Scientific Literature
8.	ALA4013444	T	Subacute toxicity in ICR mouse assessed as alteration in basic levels of SGOT at 100 to 1000 mg/kg, administered once a day via oral gavage for 14 days	Mus musculus	1		organism-based format	Scientific Literature
9.	ALA4013445	A	Drug metabolism in human HuH7 cells assessed as nucleoside diphosphate kinase-mediated ((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate metabolite formation at 50 uM after 48 hrs by LC/MS/MS analysis	Homo sapiens	1		cell-based format	Scientific Literature
10.	ALA4013446	A	Drug metabolism in human HuH7 cells assessed as UMP-CMP kinase-mediated ((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl dihydrogen phosphate metabolite formation at 50 uM after 48 hrs by LC/MS/MS analysis	Homo sapiens	1		cell-based format	Scientific Literature
11.	ALA4013447	A	Drug metabolism in human HuH7 cells assessed as carboxylesterase 1-mediated (S)-2-((R)-(((2R,3R,4R,5R)-5-(4-butyramido-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphorylamino)propanoic acid metabolite formation at 50 uM after 24 hrs by LC/MS/MS analysis	Homo sapiens	1		cell-based format	Scientific Literature
12.	ALA4013448	A	Drug metabolism in human HuH7 cells assessed as carboxylesterase-mediated (S)-2-((S)-(((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryloxy)propanoic acid metabolite formation at 50 uM after 24 hrs by LC/MS/MS analysis	Homo sapiens	1		cell-based format	Scientific Literature
13.	ALA4013449	A	Drug metabolism in human HuH7 cells assessed as HINT1-mediated ((2R,3R,4R,5R)-5-(4-butyramido-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl dihydrogen phosphate metabolite formation at 50 uM after 48 hrs by LC/MS/MS analysis	Homo sapiens	1		cell-based format	Scientific Literature
14.	ALA4013450	A	Drug metabolism in human HuH7 cells assessed as carboxylesterase-mediated (S)-2-((S)-(((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryloxy)propanoic acid metabolite formation at 50 uM after 48 hrs by LC/MS/MS analysis	Homo sapiens	1		cell-based format	Scientific Literature
15.	ALA4013451	A	Tmax in Beagle dog at 150 mg/kg, administered via oral gavage measured up to 24 hrs post dose by LC/MS/MS analysis	Canis lupus familiaris	1		organism-based format	Scientific Literature
16.	ALA4013452	T	Acute toxicity in ICR mouse assessed as mortality at 150 to 1800 mg/kg, administered via oral gavage measured once a day over 14 days	Mus musculus	1		organism-based format	Scientific Literature
17.	ALA4013453	B	Inhibition of wild type NS5B in HCV genotype 1b replicon expressed in human HuH7 cells after 72 hrs by bright Glo-luciferase reporter gene assay	Hepatitis C virus subtype 1b	32		cell-based format	Scientific Literature
18.	ALA4013454	A	Cytotoxicity against human HuH7 cells assessed as reduction in cell viability up to 100 uM after 72 hrs by Cell Titer-Fluor Cell assay	Homo sapiens	32		cell-based format	Scientific Literature
19.	ALA4013455	B	Inhibition of NS5B S282T mutant in HCV genotype 1b replicon expressed in human HuH7 cells after 72 hrs by bright Glo-luciferase reporter gene assay	Hepatitis C virus subtype 1b	3		cell-based format	Scientific Literature
20.	ALA4013456	B	Ratio of EC50 for HCV genotype 1b replicon NS5B S282T mutant to EC50 for wild type HCV genotype 1b replicon NS5B	Hepatitis C virus subtype 1b	3		assay format	Scientific Literature