# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4046960 | Functional | Cytotoxicity against human NCI-H23 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay | Homo sapiens | 22 | ALA4043212 | cell-based format | Scientific Literature | |
2. | ALA4046961 | Functional | Cytotoxicity against human HCT15 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay | Homo sapiens | 22 | ALA4043212 | cell-based format | Scientific Literature | |
3. | ALA4046962 | Functional | Cytotoxicity against human NUGC3 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay | Homo sapiens | 22 | ALA4043212 | cell-based format | Scientific Literature | |
4. | ALA4046963 | Functional | Cytotoxicity against human ACHN cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay | Homo sapiens | 22 | ALA4043212 | cell-based format | Scientific Literature | |
5. | ALA4046964 | Functional | Cytotoxicity against human PC3 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay | Homo sapiens | 22 | ALA4043212 | cell-based format | Scientific Literature | |
6. | ALA4046965 | Functional | Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay | Homo sapiens | 22 | ALA4043212 | cell-based format | Scientific Literature | |
7. | ALA4046966 | Binding | Inhibition of human topoisomerase-2 alpha assessed as reduction in conversion of super coiled plasmid DNA to relaxed DNA at 100 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 4 | ALA4043212 | single protein format | Scientific Literature | |
8. | ALA4046967 | Binding | Inhibition of human topoisomerase-2 alpha assessed as reduction in conversion of super coiled plasmid DNA to relaxed DNA at 20 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 2 | ALA4043212 | single protein format | Scientific Literature | |
9. | ALA4046968 | Binding | Potency index, ratio of inhibitory activity of etoposide to test compound for inhibition of human topoisomerase-2 alpha at 100 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 1 | ALA4043212 | single protein format | Scientific Literature | |
10. | ALA4046969 | Binding | Potency index, ratio of inhibitory activity of etoposide to test compound for inhibition of human topoisomerase-2 alpha at 20 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 1 | ALA4043212 | single protein format | Scientific Literature |