#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4022773	Binding	Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substrate assessed as decrease in IMP levels after 1 hr by mass spectrometric method	Homo sapiens	19	ALA4020815	assay format	Scientific Literature
2.	ALA4022774	Binding	Inhibition of AICARFT in human NCI-H460 cells assessed as increase in ZMP levels using low folate media after 16 hrs by LC-MS method	Homo sapiens	18	ALA4020815	cell-based format	Scientific Literature
3.	ALA4022780	ADME	Permeability across apical to basolateral side in MDCK cells at 20 uM	Canis lupus familiaris	14	ALA4020815	cell-based format	Scientific Literature
4.	ALA4022784	ADME	Plasma concentration in CD-1 mouse at 10 mg/kg, po after 1 hr by LC-MS/MS method	Mus musculus	12	ALA4020815	organism-based format	Scientific Literature
5.	ALA4022785	ADME	Fraction unbound in CD-1 mouse plasma	Mus musculus	12	ALA4020815	cell-free format	Scientific Literature
6.	ALA4022797	ADME	Unbound clearance in CD-1 mouse at 5 mg/kg, iv by LC-MS/MS method	Mus musculus	3	ALA4020815	organism-based format	Scientific Literature
7.	ALA4022798	ADME	Unbound volume of distribution at steady state in CD-1 mouse at 5 mg/kg, iv by LC-MS/MS method	Mus musculus	3	ALA4020815	organism-based format	Scientific Literature
8.	ALA4022799	ADME	Unbound AUC in CD-1 mouse at 5 mg/kg, po by LC-MS/MS method	Mus musculus	3	ALA4020815	organism-based format	Scientific Literature
9.	ALA4022800	ADME	Half life in CD-1 mouse at 5 mg/kg, po by LC-MS/MS method	Mus musculus	3	ALA4020815	organism-based format	Scientific Literature
10.	ALA4022801	ADME	Unbound Cmax in CD-1 mouse at 5 mg/kg, po by LC-MS/MS method	Mus musculus	3	ALA4020815	organism-based format	Scientific Literature
11.	ALA4022802	ADME	Oral bioavailability in CD-1 mouse at 5 mg/kg by LC-MS/MS method	Mus musculus	3	ALA4020815	organism-based format	Scientific Literature