# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4044906 | F | Antiobesity activity in mouse 3T3L1 cells assessed as increase in glycerol release after 24 hrs | Mus musculus | 2 | cell-based format | Scientific Literature | ||
2. | ALA4044907 | F | Antiobesity activity in mouse 3T3L1 cells assessed as reduction in accumulation of lipid droplets administered on day 4 post differentiation induction measured on day 9 by Oil Red O staining-based microscopic analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
3. | ALA4044908 | A | Cytotoxicity against mouse 3T3L1 cells assessed as reduction in cell viability up to 100 uM after 6 to 48 hrs by CCK-8 assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
4. | ALA4044909 | B | Activation of PKA in mouse 3T3-L1 cells assessed as lipolytic activity by measuring increase in glycerol release at 25 uM administered 1 hr after PKA inhibitor addition measured after 24 hrs in presence of 20 uM PKA inhibitor H-89 | Mus musculus | 2 | cell-based format | Scientific Literature | ||
5. | ALA4044910 | B | Activation of ERK in mouse 3T3-L1 cells assessed as lipolytic activity by measuring increase in glycerol release at 25 uM administered 1 hr after ERK inhibitor addition measured after 24 hrs in presence of 20 uM ERK inhibitor PD 98059 | Mus musculus | 2 | cell-based format | Scientific Literature | ||
6. | ALA4044911 | B | Activation of beta3 adrenergic receptor in mouse 3T3-L1 cells assessed as lipolytic activity by measuring increase in glycerol release at 25 uM administered 1 hr after beta3 adrenergic receptor inhibitor addition measured after 24 hrs in presence of 20 uM PKA inhibitor propranolol | Mus musculus | 2 | cell-based format | Scientific Literature | ||
7. | ALA4044912 | B | Induction of PKA phosphorylation in mouse 3T3-L1 cells at 12.5 uM in presence of 20 uM H-89 by immunoblotting | Mus musculus | 2 | cell-based format | Scientific Literature |