# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4017715 | ADME | AUC (0 to infinity) in Swiss mouse plasma at 2 mg/kg, iv | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature | |
2. | ALA4017716 | ADME | Oral bioavailability in Swiss mouse plasma at 10 mg/kg | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature | |
3. | ALA4017717 | Binding | Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporter gene assay | Homo sapiens | 5 | ALA4017455 | assay format | Scientific Literature | |
4. | ALA4017718 | Binding | Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranes | Homo sapiens | 6 | ALA4017455 | cell-based format | Scientific Literature | |
5. | ALA4017720 | Functional | Antiproliferative activity against human MDA-MB-468 cells at 3 to 20 uM by CellTiter-Glo assay | Homo sapiens | 3 | ALA4017455 | cell-based format | Scientific Literature | |
6. | ALA4017721 | ADME | Protein binding in mouse plasma | Mus musculus | 3 | ALA4017455 | cell-free format | Scientific Literature | |
7. | ALA4017722 | ADME | Protein binding in human plasma | Homo sapiens | 3 | ALA4017455 | cell-free format | Scientific Literature | |
8. | ALA4017723 | ADME | Stability in mouse plasma | Mus musculus | 3 | ALA4017455 | cell-free format | Scientific Literature | |
9. | ALA4017724 | ADME | Stability in human plasma | Homo sapiens | 3 | ALA4017455 | cell-free format | Scientific Literature | |
10. | ALA4017725 | ADME | Stability in mouse liver microsomes | Mus musculus | 3 | ALA4017455 | assay format | Scientific Literature | |
11. | ALA4017726 | ADME | Stability in human liver microsomes | Homo sapiens | 3 | ALA4017455 | assay format | Scientific Literature | |
12. | ALA4017727 | Physicochemical | Solubility of compound in PBS buffer at pH 7.4 | 3 | ALA4017455 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA4017728 | ADME | Cmax in Swiss mouse plasma at 10 mg/kg, ip | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature | |
14. | ALA4017729 | ADME | Tmax in Swiss mouse plasma at 10 mg/kg, ip | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature | |
15. | ALA4017730 | ADME | AUC (0 to t) in Swiss mouse plasma at 10 mg/kg, ip | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature | |
16. | ALA4017731 | ADME | AUC (0 to infinity) in Swiss mouse plasma at 10 mg/kg, ip | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature | |
17. | ALA4017732 | ADME | Half life in Swiss mouse plasma at 10 mg/kg, ip | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature | |
18. | ALA4017733 | ADME | Cmax in Swiss mouse brain at 10 mg/kg, ip | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature | |
19. | ALA4017734 | ADME | Tmax in Swiss mouse brain at 10 mg/kg, ip | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature | |
20. | ALA4017735 | ADME | AUC (0 to t) in Swiss mouse brain at 10 mg/kg, ip | Mus musculus | 1 | ALA4017455 | organism-based format | Scientific Literature |