# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4040274 | F | Cytoprotective activity in rat INS-1 cells assessed as protection against tunicamycin-induced ER stress-mediated reduction in cell viability after 3 days by CellTiter-Glo assay | Rattus norvegicus | 42 | ALA4038317 | cell-based format | Scientific Literature | |
2. | ALA4040275 | F | Cytoprotective activity in rat INS-1 cells assessed as protection against tunicamycin-induced ER stress-mediated reduction in cell viability after 3 days by CellTiter-Glo assay relative tunicamycin | Rattus norvegicus | 47 | ALA4038317 | cell-based format | Scientific Literature | |
3. | ALA4040290 | B | Inhibition of tunicamycin ER stress-induced PERK activation in rat INS-1 cells assessed as suppression of tunicamycin-induced increase in ATF4 protein levels up to 10 uM after 8 hrs by Western blot analysis | Rattus norvegicus | 2 | ALA4038317 | cell-based format | Scientific Literature | |
4. | ALA4040291 | B | Inhibition of tunicamycin ER stress-induced PERK activation in rat INS-1 cells assessed as suppression of tunicamycin-induced increase in CHOP protein levels up to 10 uM after 8 hrs by Western blot analysis | Rattus norvegicus | 2 | ALA4038317 | cell-based format | Scientific Literature | |
5. | ALA4040293 | B | Inhibition of tunicamycin ER stress-induced ATF6 activation in rat INS-1 cells assessed as suppression of increase in Bip mRNA levels up to 10 uM after 8 hrs by qRT-PCR analysis | Rattus norvegicus | 2 | ALA4038317 | cell-based format | Scientific Literature | |
6. | ALA4040294 | B | Inhibition of tunicamycin ER stress-induced ATF6 activation in rat INS-1 cells assessed as suppression of increase in GPR94 mRNA levels up to 10 uM after 8 hrs by qRT-PCR analysis | Rattus norvegicus | 2 | ALA4038317 | cell-based format | Scientific Literature |