| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4032440 | B | Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA4032441 | B | Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 3. | ALA4032442 | B | Selectivity ratio of Ki for human dopamine D2 long receptor to Ki for human dopamine D3 receptor | Homo sapiens | 15 | assay format | Scientific Literature | ||
| 4. | ALA4032443 | B | Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA4032444 | B | Binding affinity to 5-HT2A receptor (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA4032445 | B | Binding affinity to 5-HT2C receptor (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA4032448 | F | Partial agonist activity at human dopamine D3 receptor expressed in human U2OS cells assessed as inhibition of forskolin-dependent stimulation of adenylyl cyclase at 10 times Ki | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4397354 | B | Displacement of [3H]-DAMGO from human MOR stably expressed in HEK cell membranes at 10 uM after 90 mins by microbeta scintillation counting method relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4397355 | B | Displacement of [3H]-DADLE from human DOR stably expressed in HEK cell membranes at 10 uM after 90 mins by microbeta scintillation counting method relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4397356 | B | Displacement of [125I]IABN from recombinant human D3 receptor stably expressed in HEK293 cell membranes measured after 60 mins by scintillation counting analysis | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 11. | ALA4397357 | A | Displacement of [125I]IABN from recombinant human D2 long receptor stably expressed in HEK293 cell membranes measured after 60 mins by scintillation counting analysis | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 12. | ALA4397358 | B | Selectivity ratio of Ki for displacement of [125I]IABN from recombinant human D2 long receptor stably expressed in HEK293 cell membranes to Ki for displacement of [125I]IABN from recombinant human D3 receptor stably expressed in HEK293 cell membranes | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
| 13. | ALA4397359 | B | Agonist activity at recombinant human D3 receptor expressed in CHOK1 cells assessed as induction of beta arrestin2 recruitment measured after 30 mins by coelenterazine-based beta-galactosidase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4397360 | A | Antagonist activity at recombinant human D3 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta arrestin2 recruitment preincubated for 30 mins followed by dopamine addition and measured after 90 mins by coelenterazine-based beta-galactosidase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4397361 | A | Agonist activity at recombinant human D2 receptor expressed in CHOK1 cells assessed as induction of beta arrestin2 recruitment measured after 30 mins by coelenterazine-based beta-galactosidase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4397362 | A | Antagonist activity at recombinant human D2 receptor expressed in CHOK1 cells assessed as inhibition of quinpirole-induced beta arrestin2 recruitment preincubated for 30 mins followed by quinpirole addition and measured after 90 mins by coelenterazine-based beta-galactosidase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4397363 | B | Agonist activity at recombinant human D1 receptor expressed in CHOK1 cells assessed as induction of beta arrestin2 recruitment measured after 30 mins by coelenterazine-based beta-galactosidase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4397367 | B | Selectivity ratio of IC50 for recombinant human D2 receptor expressed in CHOK1 cells to IC50 for recombinant human D3 receptor expressed in CHOK1 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4397368 | B | Displacement of [3H]SCH23390 from recombinant human D1 receptor transiently expressed in HEKT cells at 10 uM measured after 90 mins by microbeta scintillation counting method relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4397369 | A | Displacement of [3H]N-methylspiperone from recombinant human D2 receptor stably expressed in fibroblast at 10 uM measured after 90 mins by microbeta scintillation counting method relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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