#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3998010	Binding	Activation of PXR in human LS180 cells assessed as P-gp induction by measuring intracellular accumulation of rhodamine 123 per ug of total protein at 5 uM preincubated for 48 hrs followed by rhodamine 123 addition after 40 mins and measured after 90 mins by fluorescence assay relative to control	Homo sapiens	29	ALA3997764	cell-based format	Scientific Literature
2.	ALA3998011	ADME	Cytotoxicity against human LS180 cells assessed as cell viability at 30 uM after 24 hrs by MTT assay relative to control	Homo sapiens	29	ALA3997764	cell-based format	Scientific Literature
3.	ALA3998012	Binding	Activation of PXR in human LS180 cells assessed as induction of P-gp expression at 5 uM by Western blot method relative to control	Homo sapiens	2	ALA3997764	cell-based format	Scientific Literature
4.	ALA3998013	Binding	Activation of PXR in human LS180 cells assessed as P-gp induction by measuring intracellular accumulation of rhodamine 123 preincubated for 48 hrs followed by rhodamine 123 addition after 40 mins and measured after 90 mins by fluorescence assay	Homo sapiens	4	ALA3997764	cell-based format	Scientific Literature
5.	ALA3998014	Physicochemical	Thermodynamic aqueous solubility of the compound in water after overnight incubation		3	ALA3997764	small-molecule physicochemical format	Scientific Literature
6.	ALA3998015	Physicochemical	Thermodynamic aqueous solubility of the compound in phosphate buffered saline at pH 7.4 after overnight incubation		3	ALA3997764	small-molecule physicochemical format	Scientific Literature
7.	ALA3998016	Physicochemical	Thermodynamic aqueous solubility of the compound in simulated gastric fluid at pH 1.2 after overnight incubation		3	ALA3997764	small-molecule physicochemical format	Scientific Literature
8.	ALA3998017	Physicochemical	Thermodynamic aqueous solubility of the compound in simulated intestinal fluid at pH 6.8 after overnight incubation		3	ALA3997764	small-molecule physicochemical format	Scientific Literature
9.	ALA3998018	ADME	Inhibition of human recombinant CYP3A4 at 10 uM by fluorescence analysis relative to control	Homo sapiens	1	ALA3997764	single protein format	Scientific Literature
10.	ALA3998019	ADME	Inhibition of human recombinant CYP2D6 at 10 uM by fluorescence analysis relative to control	Homo sapiens	1	ALA3997764	single protein format	Scientific Literature
11.	ALA3998020	ADME	Inhibition of human recombinant CYP2C9 at 10 uM by fluorescence analysis relative to control	Homo sapiens	1	ALA3997764	single protein format	Scientific Literature
12.	ALA3998021	ADME	Inhibition of human recombinant CYP2C19 at 10 uM by fluorescence analysis relative to control	Homo sapiens	1	ALA3997764	single protein format	Scientific Literature
13.	ALA3998022	ADME	Efflux ratio of permeability in human Caco2 cells after 90 mins by LC-MS/MS analysis	Homo sapiens	1	ALA3997764	cell-based format	Scientific Literature
14.	ALA3998023	ADME	Terminal half life in BALB/c mouse plasma at 1 mg/kg, iv by LC-MS/MS analysis	Mus musculus	1	ALA3997764	organism-based format	Scientific Literature
15.	ALA3998024	ADME	AUC (0 to t) in BALB/c mouse plasma at 1 mg/kg, iv up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA3997764	organism-based format	Scientific Literature
16.	ALA3998025	ADME	AUC (0 to infinity) in BALB/c mouse plasma at 1 mg/kg, iv up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA3997764	organism-based format	Scientific Literature
17.	ALA3998026	ADME	Cmax in BALB/c mouse plasma at 1 mg/kg, iv up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA3997764	organism-based format	Scientific Literature
18.	ALA3998027	ADME	Clearance in BALB/c mouse plasma at 1 mg/kg, iv up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA3997764	organism-based format	Scientific Literature
19.	ALA3998028	ADME	Initial plasma concentration in BALB/c mouse at 1 mg/kg, iv up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA3997764	organism-based format	Scientific Literature
20.	ALA3998029	ADME	Volume of distribution in BALB/c mouse at 1 mg/kg, iv up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA3997764	organism-based format	Scientific Literature