# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4040853 | B | Displacement of [35S]TBPS from GABA-A receptor in Sprague-Dawley rat cerebral cortex cell membranes after 90 mins in presence of GABA by liquid scintillation counting | Rattus norvegicus | 21 | ALA4038335 | assay format | Scientific Literature | |
2. | ALA4040854 | B | Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-mediated increase in channel current under holding potential at -80 mV preincubated for 30 secs followed by GABA stimulation for 2 secs by automated patch clamp assay | Homo sapiens | 21 | ALA4038335 | cell-based format | Scientific Literature | |
3. | ALA4040855 | B | Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-mediated increase in channel current under holding potential at -80 mV at 0.01 to 10 uM preincubated for 30 secs followed by GABA stimulation for 2 secs by automated patch clamp assay relative to GABA | Homo sapiens | 21 | ALA4038335 | cell-based format | Scientific Literature | |
4. | ALA4040856 | B | Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated increase in channel current under holding potential at -80 mV preincubated for 30 secs followed by GABA stimulation for 2 secs by manual patch clamp assay | Homo sapiens | 21 | ALA4038335 | cell-based format | Scientific Literature | |
5. | ALA4040857 | B | Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated increase in channel current under holding potential at -80 mV at 0.01 to 10 uM preincubated for 30 secs followed by GABA stimulation for 2 secs by manual patch clamp assay relative to GABA | Homo sapiens | 21 | ALA4038335 | cell-based format | Scientific Literature |