# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4042886 | Binding | Transrepression activity at glucocorticoid receptorin human HeLa cells assessed as inhibition of TPA-induced collagenase promoter activity by luciferase reporter gene assay | Homo sapiens | 12 | ALA4041544 | cell-based format | Scientific Literature | |
2. | ALA4042887 | Binding | Transrepression activity at glucocorticoid receptor in human HeLa cells assessed as inhibition of TPA-induced collagenase promoter activity by luciferase reporter gene assay relative to dexamethasone | Homo sapiens | 11 | ALA4041544 | cell-based format | Scientific Literature | |
3. | ALA4042888 | ADME | Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene assay | Homo sapiens | 12 | ALA4041544 | cell-based format | Scientific Literature | |
4. | ALA4042889 | ADME | Transactivation activity at glucocorticoid receptor in human HeLa cells assessed as induction of MMTV promoter activity by luciferase reporter gene assay relative to dexamethasone | Homo sapiens | 11 | ALA4041544 | cell-based format | Scientific Literature | |
5. | ALA4042890 | Binding | Transrepression activity at glucocorticoid receptor in human THP1 cells assessed as receptor-mediated anti-inflammatory activity by measuring inhibition of LPS-induced IL-8 production | Homo sapiens | 12 | ALA4041544 | cell-based format | Scientific Literature | |
6. | ALA4042891 | Binding | Transrepression activity at glucocorticoid receptor in human THP1 cells assessed as receptor-mediated anti-inflammatory activity by measuring inhibition of LPS-induced IL-8 production relative to dexamethasone | Homo sapiens | 11 | ALA4041544 | cell-based format | Scientific Literature | |
7. | ALA4042892 | Binding | Binding affinity to recombinant human glucocorticoid receptor expressed in baculovirus infected sf9 cells | Homo sapiens | 12 | ALA4041544 | cell-based format | Scientific Literature | |
8. | ALA4042893 | Binding | Binding affinity to recombinant human progesterone receptor expressed in baculovirus infected sf9 cells | Homo sapiens | 12 | ALA4041544 | cell-based format | Scientific Literature | |
9. | ALA4042894 | Binding | Binding affinity to recombinant human mineralocorticoid receptor expressed in baculovirus infected sf9 cells | Homo sapiens | 12 | ALA4041544 | cell-based format | Scientific Literature | |
10. | ALA4042895 | Binding | Binding affinity to recombinant human androgen receptor expressed in baculovirus infected sf9 cells | Homo sapiens | 12 | ALA4041544 | cell-based format | Scientific Literature | |
11. | ALA4042896 | ADME | Stability in human liver microsomes assessed as drug recovery after 30 mins | Homo sapiens | 12 | ALA4041544 | assay format | Scientific Literature |