# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4034964 | Functional | Growth inhibition of human HepG2 cells after 48 hrs by SRB assay | Homo sapiens | 5 | ALA4033655 | cell-based format | Scientific Literature | |
2. | ALA4034965 | Binding | Inhibition of Chk2 (unknown origin) by ELISA based spectrophotometric analysis | Homo sapiens | 11 | ALA4033655 | single protein format | Scientific Literature | |
3. | ALA4034966 | Functional | Growth inhibition of human HeLa cells after 48 hrs by SRB assay | Homo sapiens | 6 | ALA4033655 | cell-based format | Scientific Literature | |
4. | ALA4034967 | Functional | Growth inhibition of human MCF7 cells after 48 hrs by SRB assay | Homo sapiens | 7 | ALA4033655 | cell-based format | Scientific Literature | |
5. | ALA4034968 | Functional | Potentiation of doxorubicin-induced cytotoxicity against human MCF7 cells assessed as doxorubicin GI50 after 48 hrs by SRB assay | Homo sapiens | 6 | ALA4033655 | cell-based format | Scientific Literature | |
6. | ALA4034969 | Functional | Potentiation of cisplatin-induced cytotoxicity against human MCF7 cells assessed as cisplatin GI50 after 48 hrs by SRB assay | Homo sapiens | 6 | ALA4033655 | cell-based format | Scientific Literature | |
7. | ALA4034970 | Functional | Potentiating index, ratio of compound GI50 against human MCF7 cells to compound GI50 in combination with doxorubicin against human MCF7 | Homo sapiens | 6 | ALA4033655 | cell-based format | Scientific Literature | |
8. | ALA4034971 | Functional | Potentiating index, ratio of compound GI50 against human MCF7 cells to compound GI50 in combination with cisplatin against human MCF7 | Homo sapiens | 6 | ALA4033655 | cell-based format | Scientific Literature | |
9. | ALA4034972 | Binding | Inhibition of Chk2 (unknown origin) at 2.5 umol/L by ELISA based spectrophotometric analysis relative to control | Homo sapiens | 11 | ALA4033655 | single protein format | Scientific Literature | |
10. | ALA4034973 | Binding | Inhibition of Chk2 (unknown origin) at 1.5 umol/L by ELISA based spectrophotometric analysis relative to control | Homo sapiens | 11 | ALA4033655 | single protein format | Scientific Literature | |
11. | ALA4034974 | Binding | Inhibition of Chk2 (unknown origin) at 0.1 umol/L by ELISA based spectrophotometric analysis relative to control | Homo sapiens | 11 | ALA4033655 | single protein format | Scientific Literature | |
12. | ALA4034975 | Binding | Inhibition of Chk2 (unknown origin) at 0.050 umol/L by ELISA based spectrophotometric analysis relative to control | Homo sapiens | 11 | ALA4033655 | single protein format | Scientific Literature | |
13. | ALA4034976 | Binding | Inhibition of Chk2 (unknown origin) at 0.025 umol/L by ELISA based spectrophotometric analysis relative to control | Homo sapiens | 11 | ALA4033655 | single protein format | Scientific Literature | |
14. | ALA4034978 | Functional | Cell cycle arrest in human MCF7 cells assessed as accumulation at G1 phase at 0.1 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 75.09%) | Homo sapiens | 2 | ALA4033655 | cell-based format | Scientific Literature | |
15. | ALA4034979 | Functional | Cell cycle arrest in human MCF7 cells assessed as accumulation at G1 phase at 0.1 uM after 48 hrs in presence of 4.2 uM doxorubicin by propidium iodide staining based flow cytometry (Rvb = 75.09%) | Homo sapiens | 2 | ALA4033655 | cell-based format | Scientific Literature | |
16. | ALA4034981 | Functional | Cell cycle arrest in human MCF7 cells assessed as accumulation at S phase at 0.1 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 17.24%) | Homo sapiens | 2 | ALA4033655 | cell-based format | Scientific Literature | |
17. | ALA4034982 | Functional | Cell cycle arrest in human MCF7 cells assessed as accumulation at S phase at 0.1 uM after 48 hrs in presence of 4.2 uM doxorubicin by propidium iodide staining based flow cytometry (Rvb = 17.24%) | Homo sapiens | 2 | ALA4033655 | cell-based format | Scientific Literature | |
18. | ALA4034984 | Functional | Cell cycle arrest in human MCF7 cells assessed as accumulation at G2/M phase at 0.1 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 7.67%) | Homo sapiens | 2 | ALA4033655 | cell-based format | Scientific Literature | |
19. | ALA4034985 | Functional | Cell cycle arrest in human MCF7 cells assessed as accumulation at G2/M phase at 0.1 uM after 48 hrs in presence of 4.2 uM doxorubicin by propidium iodide staining based flow cytometry (Rvb = 7.67%) | Homo sapiens | 2 | ALA4033655 | cell-based format | Scientific Literature | |
20. | ALA4034986 | Functional | Antitumor activity against MNU-induced breast cancer in Sprague-Dawley rat assessed as histological alterations in mammary gland sections at 0.1 times LD50 administered orally for 10 consecutive days followed by single dose of doxorubicin measured after 24 hrs by hematoxylin/eosin staining based light electric microscopy | Rattus norvegicus | 1 | ALA4033655 | assay format | Scientific Literature |