# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4015173 | B | Antagonist activity at integrin alphaVbeta3 (unknown origin) expressed in HEK293 cells assessed as reduction in cell adhesion to fibrinogen after 2 hrs by MTT assay | Homo sapiens | 8 | ALA4014304 | cell-based format | Scientific Literature | |
2. | ALA4015174 | B | Antagonist activity at integrin alphaVbeta3alphaVbeta5 (unknown origin) expressed in SKOV3 cells assessed as reduction in cell adhesion to fibrinogen after 2 hrs by MTT assay | Homo sapiens | 8 | ALA4014304 | cell-based format | Scientific Literature | |
3. | ALA4015175 | B | Antagonist activity at integrin alphaVbeta5 (unknown origin) expressed in HT-29 cells assessed as reduction in cell adhesion to vitronectin after 2 hrs by MTT assay | Homo sapiens | 8 | ALA4014304 | cell-based format | Scientific Literature | |
4. | ALA4015176 | B | Selectivity ratio of IC50 for integrin alphaVbeta5 (unknown origin) expressed in HT-29 cells to IC50 for integrin alphaVbeta3 (unknown origin) expressed in HEK293 cells | Homo sapiens | 1 | ALA4014304 | cell-based format | Scientific Literature | |
5. | ALA4015177 | B | Selectivity ratio of IC50 for integrin alphaVbeta5 (unknown origin) expressed in HT-29 cells to IC50 for integrin alphaVbeta3alphaVbeta5 (unknown origin) expressed in SKOV3 cells | Homo sapiens | 1 | ALA4014304 | cell-based format | Scientific Literature |