| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4031179 | B | Binding affinity to human cGAS (2 to 522 residues) expressed in Sf9 insect cells by surface plasmon resonance assay | Homo sapiens | 6 | ALA4028860 | cell-based format | Scientific Literature | |
| 2. | ALA4031180 | B | Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presence of ATP and GTP after 30 mins by mass spectrometric analysis | Homo sapiens | 6 | ALA4028860 | cell-based format | Scientific Literature | |
| 3. | ALA4031181 | B | Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presence of ATP and GTP incubated for 1 hr followed by Cy5-labeled cGAMP addition measured after 1 hr by fluorescence polarization assay | Homo sapiens | 6 | ALA4028860 | cell-based format | Scientific Literature |
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