| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4027654 | B | Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus subsp. aureus str. Newman | 100 | ALA4024779 | single protein format | Scientific Literature | |
| 2. | ALA4027655 | B | Inhibition of CrtN in methicillin-resistant Staphylococcus aureus USA400 MW2 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus subsp. aureus MW2 | 3 | ALA4024779 | single protein format | Scientific Literature | |
| 3. | ALA4027656 | B | Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus LAC | 3 | ALA4024779 | single protein format | Scientific Literature | |
| 4. | ALA4027657 | B | Inhibition of CrtN in methicillin-resistant Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus subsp. aureus Mu50 | 3 | ALA4024779 | single protein format | Scientific Literature | |
| 5. | ALA4027658 | B | Inhibition of CrtN in methicillin-resistant Staphylococcus aureus NRS271 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pigment inhibition assay | Staphylococcus aureus | 3 | ALA4024779 | assay format | Scientific Literature | |
| 6. | ALA4027659 | A | Cytotoxicity against HEK293 cells after 43 hrs by Alamar blue dye-based fluorescence assay | Homo sapiens | 5 | ALA4024779 | cell-based format | Scientific Literature | |
| 7. | ALA4027660 | A | Cytotoxicity against human HepG2 cells after 43 hrs by Alamar blue dye-based fluorescence assay | Homo sapiens | 5 | ALA4024779 | cell-based format | Scientific Literature | |
| 8. | ALA4027661 | P | Aqueous solubility of compound after 24 hrs by HPLC method | 3 | ALA4024779 | small-molecule physicochemical format | Scientific Literature | ||
| 9. | ALA4027662 | B | Inhibition of human ERG expressed in CHO cells at -80 mV holding potential after 3 mins by QPatch test | Homo sapiens | 3 | ALA4024779 | cell-based format | Scientific Literature | |
| 10. | ALA4027663 | B | Inhibition of Staphylococcus aureus Newman 6His-tagged CrtN expressed in Escherichia coli BL21 (DE3)/pET28a::CrtN assessed as reduction in staphyloxanthin levels using diapophytoene as substrate after overnight incubation by spectrophotometric analysis | Staphylococcus aureus subsp. aureus str. Newman | 3 | ALA4024779 | assay format | Scientific Literature | |
| 11. | ALA4027664 | A | Half life in human liver microsomes at 2 uM after 60 mins in presence of NADPH by LC-MS/MS method | Homo sapiens | 3 | ALA4024779 | assay format | Scientific Literature | |
| 12. | ALA4027665 | A | In-vitro intrinsic clearance in human liver microsomes at 2 uM after 60 mins in presence of NADPH by LC-MS/MS method | Homo sapiens | 3 | ALA4024779 | assay format | Scientific Literature | |
| 13. | ALA4027666 | A | In-vivo intrinsic clearance in human liver microsomes at 2 uM after 60 mins in presence of NADPH by LC-MS/MS method | Homo sapiens | 3 | ALA4024779 | assay format | Scientific Literature | |
| 14. | ALA4027667 | F | In vitro antifungal activity against Trichophyton rubrum after 7 days by serial dilution method | Trichophyton rubrum | 6 | ALA4024779 | assay format | Scientific Literature | |
| 15. | ALA4027668 | F | In vitro antifungal activity against Microsporum gypseum after 7 days by serial dilution method | Nannizzia gypsea | 6 | ALA4024779 | assay format | Scientific Literature | |
| 16. | ALA4027669 | F | In vitro antifungal activity against Trichophyton verrucosum after 7 days by serial dilution method | Trichophyton verrucosum | 6 | ALA4024779 | assay format | Scientific Literature | |
| 17. | ALA4027670 | F | In vitro antifungal activity against Trichophyton mentagrophytes after 7 days by serial dilution method | Trichophyton mentagrophytes | 6 | ALA4024779 | assay format | Scientific Literature | |
| 18. | ALA4027671 | A | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate upto 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 2 | ALA4024779 | assay format | Scientific Literature | |
| 19. | ALA4027672 | A | Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate upto 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 2 | ALA4024779 | assay format | Scientific Literature | |
| 20. | ALA4027673 | A | Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate upto 10 uM after 20 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 2 | ALA4024779 | assay format | Scientific Literature |
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