# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3991966 | B | Inhibition of c-Myc/Max interaction in human HL60 cells assessed as cell growth inhibition after 5 days by trypan blue exclusion assay | Homo sapiens | 12 | cell-based format | Patent Bioactivity Data | ||
2. | ALA3991967 | B | Inhibition of c-Myc/Max interaction in human HL60 nuclear extracts at 100 to 200 uM after 30 mins by co-immunoprecipitation assay | Homo sapiens | 12 | protein format | Patent Bioactivity Data | ||
3. | ALA3991968 | A | Effect on absolute levels of c-Myc in human HL60 nuclear extracts at 100 to 200 uM after 30 mins by co-immunoprecipitation assay | Homo sapiens | 12 | cell-based format | Patent Bioactivity Data | ||
4. | ALA3991969 | A | Effect on absolute levels of Max in human HL60 nuclear extracts at 100 to 200 uM after 30 mins by co-immunoprecipitation assay | Homo sapiens | 12 | cell-based format | Patent Bioactivity Data | ||
5. | ALA3991970 | B | Inhibition of recombinant human His6 tagged c-Myc bHLH-LZ domain (353 to 439 residues) with GGCD extension at C-terminus/recombinant human full length His6 tagged Max (151 residues) expressed in Escherichia coli assessed as reduction of heterodimer binding to HEX labeled E-box-containing DNA after 90 mins by electrophoretic mobility shift assay | Homo sapiens | 12 | assay format | Patent Bioactivity Data | ||
6. | ALA3991971 | B | Inhibition of human His6 tagged Max (160 residues) homodimer binding to HEX labeled E-box-containing DNA after 90 mins by electrophoretic mobility shift assay | Homo sapiens | 12 | single protein format | Patent Bioactivity Data | ||
7. | ALA3991975 | B | Inhibition of c-Myc in rat TGR1 cells assessed as cell growth inhibition at 6 to 50 uM after 3 to 4 days by trypan blue exclusion assay | Rattus norvegicus | 8 | cell-based format | Patent Bioactivity Data | ||
8. | ALA3991976 | A | Cytotoxicity against rat KO-HMG cells assessed as cell growth inhibition at 6 to 50 uM after 3 to 4 days by trypan blue exclusion assay | Rattus norvegicus | 8 | cell-based format | Patent Bioactivity Data | ||
9. | ALA3991977 | F | Cytotoxicity against rat H016.4C cells assessed as cell growth inhibition at 6 to 50 uM after 3 to 9 days by trypan blue exclusion assay | Rattus norvegicus | 8 | cell-based format | Patent Bioactivity Data |