# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3994535 | Functional | Antinociceptive activity in CD-1 mouse model of thermal-induced nociception assessed as increase in latency to respond with hind paw lick or jumping at 23 nmol/mouse, icv measured 15 to 60 mins post dose by hot plate test relative to control | Mus musculus | 1 | ALA3992569 | assay format | Scientific Literature | |
2. | ALA3994536 | Binding | Displacement of [3H]lleDelt2 from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting method | Rattus norvegicus | 4 | ALA3992569 | cell membrane format | Scientific Literature | |
3. | ALA3994537 | ADME | Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting method | Rattus norvegicus | 4 | ALA3992569 | cell membrane format | Scientific Literature | |
4. | ALA3994538 | Unassigned | Selectivity index, ratio of Ki for mu opioid receptor in Wistar rat brain membranes to Ki for delta opioid receptor in Wistar rat brain membranes | Rattus norvegicus | 4 | ALA3992569 | cell membrane format | Scientific Literature | |
5. | ALA3994539 | Functional | Antinociceptive activity in CD-1 mouse model of thermal-induced nociception assessed as increase in latency to tail withdrawal at 23 nmol/mouse, icv measured 15 to 60 mins post dose by tail flick test relative to control | Mus musculus | 1 | ALA3992569 | assay format | Scientific Literature | |
6. | ALA3994542 | Functional | Analgesic activity in CD-1 mouse model of formalin-induced pain assessed as increase in latency to respond with hind paw lick or biting at 150 nmol/mouse, sc administered 15 mins prior to formalin injection measured up to 40 mins post dose | Mus musculus | 2 | ALA3992569 | organism-based format | Scientific Literature |