| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4004311 | B | Inhibition of human ROMK expressed in HEK293 cells after 30 mins by thallium flux assay | Homo sapiens | 22 | ALA4002630 | cell-based format | Scientific Literature | |
| 2. | ALA4004312 | B | Displacement of [35S]MK499 from human ERG expressed in HEK293 cells | Homo sapiens | 22 | ALA4002630 | cell-based format | Scientific Literature | |
| 3. | ALA4004313 | B | Selectivity ratio of IC50 for human ERG expressed in HEK293 cells to IC50 for human ROMK expressed in HEK293 cells | Homo sapiens | 19 | ALA4002630 | cell-based format | Scientific Literature | |
| 4. | ALA4004314 | A | Clearance in rat at 0.5 mg/kg, iv or 1 mg/kg, po administered as single dose | Rattus norvegicus | 7 | ALA4002630 | organism-based format | Scientific Literature | |
| 5. | ALA4004315 | A | Dose normalized AUC in rat at 1 mg/kg, po administered as single dose | Rattus norvegicus | 7 | ALA4002630 | organism-based format | Scientific Literature | |
| 6. | ALA4004316 | A | Volume of distribution in rat at 0.5 mg/kg, iv or 1 mg/kg, po administered as single dose | Rattus norvegicus | 7 | ALA4002630 | organism-based format | Scientific Literature | |
| 7. | ALA4004317 | A | Half life in rat at 0.5 mg/kg, iv or 1 mg/kg, po administered as single dose | Rattus norvegicus | 7 | ALA4002630 | organism-based format | Scientific Literature | |
| 8. | ALA4004318 | A | Oral bioavailability in rat at 1 mg/kg administered as single dose | Rattus norvegicus | 7 | ALA4002630 | organism-based format | Scientific Literature | |
| 9. | ALA4004320 | B | Inhibition of human ROMK expressed in CHO cells by electrophysiology method | Homo sapiens | 5 | ALA4002630 | cell-based format | Scientific Literature | |
| 10. | ALA4004321 | B | Inhibition of human ERG by electrophysiology method | Homo sapiens | 5 | ALA4002630 | single protein format | Scientific Literature | |
| 11. | ALA4004322 | B | Selectivity ratio of IC50 for human ERG to IC50 for human ROMK expressed in CHO cells by electrophysiology method | Homo sapiens | 5 | ALA4002630 | cell-based format | Scientific Literature | |
| 12. | ALA4004323 | F | Antihypertensive activity in rat spontaneous hypertensive model assessed as change in systolic blood pressure at 3 mg/kg, po measured after 3 days | Rattus norvegicus | 5 | ALA4002630 | organism-based format | Scientific Literature | |
| 13. | ALA4004325 | A | Drug uptake in plasma of rat spontaneous hypertensive model at 3 mg/kg, po measured after 3 days | Rattus norvegicus | 5 | ALA4002630 | organism-based format | Scientific Literature | |
| 14. | ALA4004328 | B | Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by thallium flux assay | Rattus norvegicus | 5 | ALA4002630 | cell-based format | Scientific Literature |
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