#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4055361	Binding	Displacement of (5-(6-(10H-spiro(1-benzofuran-3,30-pyrrolidin)-10-yl)pyridazin-3-yl)-1,2,4-oxadiazol-3-yl)[3H2]methanol from SCD1 in human liver microsomes after 120 mins TopCount liquid scintillation counting method	Homo sapiens	17	ALA4052653	assay format	Scientific Literature
2.	ALA4055362	ADME	Fraction unbound in mouse plasma	Mus musculus	4	ALA4052653	cell-free format	Scientific Literature
3.	ALA4055363	Functional	Growth inhibition of human HCT116 cells after 72 hrs by CellTiter-Glo luminescence assay	Homo sapiens	17	ALA4052653	cell-based format	Scientific Literature
4.	ALA4055364	ADME	Stability in human liver microsomes	Homo sapiens	10	ALA4052653	assay format	Scientific Literature
5.	ALA4055365	ADME	Stability in mouse liver microsomes	Mus musculus	10	ALA4052653	assay format	Scientific Literature
6.	ALA4055366	ADME	Total clearance in mouse at 0.1 mg/kg, iv or 1 mg/kg, po administered as cassette dose	Mus musculus	4	ALA4052653	organism-based format	Scientific Literature
7.	ALA4055367	ADME	AUC in po dosed mouse administered as cassette dose	Mus musculus	4	ALA4052653	organism-based format	Scientific Literature
8.	ALA4055368	ADME	Mean residence time in po dosed mouse administered as cassette dose	Mus musculus	4	ALA4052653	organism-based format	Scientific Literature
9.	ALA4055369	Functional	In-vivo inhibition of SCD1 in athymic nude mouse xenografted with human HCT116 cells assessed as decrease in desaturation index of phosphatidylcholine at 0.3 to 30 mg/kg, po bid measured after 16 hrs by LC/MS analysis	Mus musculus	1	ALA4052653	organism-based format	Scientific Literature
10.	ALA4055370	Functional	Antitumor activity against human 786-O cells xenografted in athymic BALB/cA Jc1-nu/nu mouse assessed as tumor growth inhibition at 1 mg/kg, po bid administered for 28 days measured twice per week	Homo sapiens	1	ALA4052653	organism-based format	Scientific Literature
11.	ALA4055371	Toxicity	Toxicity in athymic BALB/cA Jc1-nu/nu mouse at 1 mg/kg, po bid administered for 28 days	Mus musculus	1	ALA4052653	organism-based format	Scientific Literature