| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4051945 | Functional | Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assay relative to lithocholic acid | Homo sapiens | 27 | ALA4049444 | cell-based format | Scientific Literature | |
| 2. | ALA4051946 | Functional | Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assay | Homo sapiens | 32 | ALA4049444 | cell-based format | Scientific Literature | |
| 3. | ALA4051947 | Functional | Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assay relative to lithocholic acid | Mus musculus | 28 | ALA4049444 | cell-based format | Scientific Literature | |
| 4. | ALA4051948 | Functional | Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assay | Mus musculus | 32 | ALA4049444 | cell-based format | Scientific Literature | |
| 5. | ALA4051953 | ADME | Apparent permeability from apical to basolateral side in human Caco2 cells at 10 uM after 1 hr by LC-MS/MS analysis | Homo sapiens | 3 | ALA4049444 | cell-based format | Scientific Literature | |
| 6. | ALA4051954 | ADME | Apparent permeability from basolateral to apical side in human Caco2 cells at 10 uM after 1 hr by LC-MS/MS analysis | Homo sapiens | 3 | ALA4049444 | cell-based format | Scientific Literature | |
| 7. | ALA4051978 | ADME | Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in human Caco2 cells at 10 uM after 1 hr by LC-MS/MS analysis | Homo sapiens | 4 | ALA4049444 | cell-based format | Scientific Literature |
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