# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4011333 | B | Enhancing of [3H]WIN35,428 binding to recombinant human DAT expressed in HEK293 cell membranes at 10 uM pre-incubated for 10 mins before radioligand addition and measured 90 mins after radioligand addition by micro beta scintillation counting analysis relative to control | Homo sapiens | 20 | ALA4007505 | cell-based format | Scientific Literature | |
2. | ALA4011334 | B | Inhibition of [3H]WIN35,428 binding to recombinant human DAT expressed in HEK293 cell membranes at 10 uM pre-incubated for 10 mins before radioligand addition and measured 90 mins after radioligand addition by micro beta scintillation counting analysis relative to control | Homo sapiens | 20 | ALA4007505 | cell-based format | Scientific Literature | |
3. | ALA4011335 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human A3AR expressed in HEK293T cells pre-incubated for 10 mins before radioligand addition and measured 90 mins after radioligand addition by micro beta scintillation counting analysis relative to control | Homo sapiens | 19 | ALA4007505 | cell-based format | Scientific Literature | |
4. | ALA4011336 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from mouse A3AR expressed in HEK293T cells pre-incubated for 10 mins before radioligand addition and measured 90 mins after radioligand addition by micro beta scintillation counting analysis relative to control | Mus musculus | 5 | ALA4007505 | cell-based format | Scientific Literature | |
5. | ALA4011351 | B | Inhibition of [3H]nisoxetine binding to recombinant human NET expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 1 | ALA4007505 | cell-based format | Scientific Literature | |
6. | ALA4011359 | B | Inhibition of [3H]mazindol binding to recombinant human SERT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand addition measured after 90 mins by micro beta scintillation counting analysis | Homo sapiens | 22 | ALA4007505 | cell-based format | Scientific Literature | |
7. | ALA4011361 | F | Antiallodynic activity in mouse chronic constriction injury model of neuropathic pain assessed as time duration of action for increasing in paw withdrawal threshold at 3 umol/kg, po administered on day 7 post injury | Mus musculus | 2 | ALA4007505 | organism-based format | Scientific Literature | |
8. | ALA4011363 | B | Displacement of [3H]Rauwolscine from human adrenergic alpha2A receptor | Homo sapiens | 2 | ALA4007505 | single protein format | Scientific Literature | |
9. | ALA4011364 | B | Displacement of [3H]Rauwolscine from human adrenergic alpha2B receptor | Homo sapiens | 2 | ALA4007505 | single protein format | Scientific Literature | |
10. | ALA4011369 | B | Displacement of [3H]Prazosin from human adrenergic alpha1A receptor | Homo sapiens | 3 | ALA4007505 | single protein format | Scientific Literature | |
11. | ALA4011370 | B | Displacement of [3H]Prazosin from human adrenergic alpha1B receptor | Homo sapiens | 3 | ALA4007505 | single protein format | Scientific Literature | |
12. | ALA4011371 | B | Displacement of [3H]Prazosin from human adrenergic alpha1D receptor | Homo sapiens | 3 | ALA4007505 | single protein format | Scientific Literature | |
13. | ALA4011372 | B | Displacement of [3H]Rauwolscine from human adrenergic alpha2C receptor | Homo sapiens | 3 | ALA4007505 | single protein format | Scientific Literature | |
14. | ALA4011374 | B | Enhancing of [3H]WIN35,428 binding to recombinant human DAT expressed in HEK293 cell membranes pre-incubated for 10 mins before radioligand addition and measured 90 mins after radioligand addition by micro beta scintillation counting analysis relative to control | Homo sapiens | 7 | ALA4007505 | cell-based format | Scientific Literature | |
15. | ALA4731024 | B | Displacement of [3H]N6-R-phenylisopropyladenosine from human A1AR receptor expressed in HEK293 cells assessed as inhibitory constant by radio ligand binding assay | Homo sapiens | 5 | ALA4725439 | cell-based format | Scientific Literature | |
16. | ALA4731026 | B | Displacement of [125I]AB-MECA from recombinant mouse A1AR expressed in HEK293 cells assessed as inhibitory constant by radio ligand binding assay | Mus musculus | 4 | ALA4725439 | cell-based format | Scientific Literature | |
17. | ALA4731029 | B | Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarboxamidoadenosine from human A2A receptor expressed in HEK293 cells at 10 uM by radio ligand binding assay relative to control | Homo sapiens | 10 | ALA4725439 | cell-based format | Scientific Literature | |
18. | ALA5158751 | B | Activation of human ABCG2-mediated ATPase activity preincubated for 2 mins followed by ATP addition at 2.5 M and measured after 20 mins by colorimetric assay relative to control | Homo sapiens | 10 | ALA5154735 | single protein format | Scientific Literature | |
19. | ALA5158752 | B | Activation of human ABCG2-mediated ATPase activity preincubated for 2 mins followed by ATP addition at 10 M and measured after 20 mins by colorimetric assay relative to control | Homo sapiens | 9 | ALA5154735 | single protein format | Scientific Literature | |
20. | ALA5158763 | B | Binding affinity towards human adenosine A3 receptor | Homo sapiens | 29 | ALA5154735 | single protein format | Scientific Literature |