# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4044420 | Functional | Antagonist activity at human GPR4 expressed in human HeLa cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by cAMP addition measured after 60 mins by HTRF method | Homo sapiens | 22 | ALA4043105 | cell-based format | Scientific Literature | |
2. | ALA4044423 | Functional | Antagonist activity at human TDAG8 expressed in human HeLa cells assessed as inhibition of IBMX-induced cAMP accumulation preincubated for 10 mins followed by IBMX addition measured after 15 mins by using batch column chromatography | Homo sapiens | 2 | ALA4043105 | cell-based format | Scientific Literature | |
3. | ALA4044424 | Binding | Inhibition of human cathepsin K | Homo sapiens | 2 | ALA4043105 | single protein format | Scientific Literature | |
4. | ALA4044450 | Functional | Antagonist activity at human GPR4 expressed in African green monkey COS7 cells assessed as inhibition of pH 6.5-induced cAMP accumulation at 5 uM after 30 mins by HTRF method relative to control | Homo sapiens | 2 | ALA4043105 | cell-based format | Scientific Literature | |
5. | ALA4044451 | Functional | Antagonist activity at human GPR4 expressed in African green monkey COS7 cells assessed as inhibition of pH 6.5-induced cAMP accumulation after 30 mins by HTRF method | Homo sapiens | 2 | ALA4043105 | cell-based format | Scientific Literature |