# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4035553 | F | Neuroprotective activity against serum deprivation-induced cell death in rat PC12 cells assessed as cell survival at 25 uM after 48 hrs by MTT assay relative to control | Rattus norvegicus | 6 | ALA4033680 | cell-based format | Scientific Literature | |
2. | ALA4035559 | F | Potentiation of NGF-induced neuronal differentiation in rat PC12 cells assessed as increase in number of neurites after 8 days by phase contrast micoscopy | Rattus norvegicus | 2 | ALA4033680 | cell-based format | Scientific Literature | |
3. | ALA4035560 | F | Neuroprotective activity against serum deprivation-induced cell death in rat PC12 cells assessed as increase in cell survival at 25 uM after 48 hrs in presence of TrkA inhibitor K252a by MTT assay | Rattus norvegicus | 6 | ALA4033680 | cell-based format | Scientific Literature | |
4. | ALA4035561 | B | Activation of TrkA in rat PC12 cells assessed as increase in phospho-TrkA levels at 5 to 25 uM after 60 mins by Western blot method | Rattus norvegicus | 2 | ALA4033680 | cell-based format | Scientific Literature | |
5. | ALA4035562 | B | Potentiation of NGF-induced TrkA phosphorylation in rat PC12 cells at 5 to 25 uM after 60 mins by Western blot method | Rattus norvegicus | 2 | ALA4033680 | cell-based format | Scientific Literature | |
6. | ALA4035563 | B | Increase in ERK1/2 phosphorylation in rat PC12 cells after 2 hrs by immunoblotting method | Rattus norvegicus | 2 | ALA4033680 | cell-based format | Scientific Literature | |
7. | ALA4035564 | B | Increase in AKT phosphorylation in rat PC12 cells at 5 to 25 uM after 2 hrs by immunoblotting method | Rattus norvegicus | 2 | ALA4033680 | cell-based format | Scientific Literature | |
8. | ALA4035566 | B | Increase in NGF-induced AKT phosphorylation in rat PC12 cells at 5 to 25 uM after 2 hrs by immunoblotting method | Rattus norvegicus | 2 | ALA4033680 | cell-based format | Scientific Literature | |
9. | ALA4035567 | B | Increase in NGF-induced ERK1/2 phosphorylation in rat PC12 cells at 5 to 25 uM after 2 hrs by immunoblotting method | Rattus norvegicus | 2 | ALA4033680 | cell-based format | Scientific Literature |