# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4000775 | A | Metabolic stability in CD-1 mouse liver S9 fraction assessed as UGT-mediated glucuronidation of compound by measuring compound remaining at 5 uM preincubated for 3 mins followed by UDPGA addition measured after 60 mins by HPLC/MS analysis | Mus musculus | 12 | ALA4000171 | assay format | Scientific Literature | |
2. | ALA4000776 | A | Metabolic stability in CD-1 mouse liver S9 fraction assessed as NADPH CYP450 reductase-mediated compound metabolism by measuring compound remaining in presence of NADPH at 20 uM after 30 mins by HPLC method | Mus musculus | 11 | ALA4000171 | assay format | Scientific Literature | |
3. | ALA4000777 | P | Thermodynamic solubility of the compound in phosphate buffer at pH 7.4 at 1 mg sonicated for 10 mins measured after 20 hrs by reverse phase HPLC analysis | 12 | ALA4000171 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4000778 | B | Inhibition of human platelet cytosolic phospholipase alpha-2 using 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine/1,2-dioleoyl-sn-glycerol as substrate after 60 mins by UV-HPLC method | Homo sapiens | 12 | ALA4000171 | assay format | Scientific Literature | |
5. | ALA4000779 | A | Metabolic stability in rat liver microsomes assessed as NADPH CYP450 reductase-mediated compound metabolism by measuring compound remaining in presence of NADPH at 20 uM after 30 mins by HPLC | Rattus norvegicus | 11 | ALA4000171 | assay format | Scientific Literature | |
6. | ALA4000780 | A | Metabolic stability in rat liver S9 fraction assessed as NADPH CYP450 reductase-mediated compound metabolism by measuring compound remaining in presence of NADPH at 20 uM after 30 mins by HPLC method | Rattus norvegicus | 11 | ALA4000171 | assay format | Scientific Literature | |
7. | ALA4000781 | A | Metabolic stability in Wistar rat liver S9 fraction assessed as UGT-mediated glucuronidation of compound by measuring compound remaining at 5 uM preincubated for 3 mins followed by UDPGA addition measured after 60 mins by HPLC/MS analysis | Rattus norvegicus | 12 | ALA4000171 | assay format | Scientific Literature |