# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4056693 | A | Cytotoxicity against African green monkey CV1 cells assessed as cell viability at 0.1 to 100 uM preincubated for 4 hrs measured after 24 hrs by MTT assay relative to control | Chlorocebus aethiops | 40 | ALA4052722 | cell-based format | Scientific Literature | |
2. | ALA4056694 | A | Cytotoxicity against African green monkey CV1 cells assessed as reduction in cell viability preincubated for 4 hrs measured after 24 hrs by MTT assay relative to control | Chlorocebus aethiops | 40 | ALA4052722 | cell-based format | Scientific Literature | |
3. | ALA4056695 | F | Antiviral activity against Vaccinia virus LIVP harboring GFP infected in African green monkey CV1 cells assessed as GFP expression at 10 uM preincubated for 4 hrs with cells followed by viral infection measured after 24 hrs by flow cytometric analysis relative to control | Vaccinia virus | 40 | ALA4052722 | assay format | Scientific Literature | |
4. | ALA4056696 | F | Antiviral activity against Vaccinia virus LIVP harboring GFP infected in African green monkey CV1 cells assessed as virus titer at 1 uM preincubated with cells for 4 hrs followed by viral infection measured after 48 hrs by gentian violet staining-based microscopic analysis (Rvb = 3.3 +/- 0.1 log10PFU/ml) | Vaccinia virus | 5 | ALA4052722 | assay format | Scientific Literature | |
5. | ALA4056697 | F | Antiviral activity against Vaccinia virus LIVP harboring GFP infected in African green monkey CV1 cells assessed as virus titer at 10 uM preincubated with cells for 4 hrs followed by viral infection measured after 48 hrs by gentian violet staining-based microscopic analysis (Rvb = 3.3 +/- 0.1 log10PFU/ml) | Vaccinia virus | 5 | ALA4052722 | assay format | Scientific Literature | |
6. | ALA4056698 | F | Antiviral activity against Vaccinia virus LIVP harboring GFP infected in African green monkey CV1 cells assessed as virus titer at 50 uM preincubated with cells for 4 hrs followed by viral infection measured after 48 hrs by gentian violet staining-based microscopic analysis (Rvb = 3.3 +/- 0.1 log10PFU/ml) | Vaccinia virus | 3 | ALA4052722 | assay format | Scientific Literature | |
7. | ALA4056701 | A | Cytotoxicity against African green monkey CV1 cells assessed as viable cells at 1 uM after 110 hrs by real-time cell analysis relative to control | Chlorocebus aethiops | 5 | ALA4052722 | cell-based format | Scientific Literature | |
8. | ALA4056702 | A | Cytotoxicity against African green monkey CV1 cells assessed as viable cells at 10 uM after 110 hrs by real-time cell analysis relative to control | Chlorocebus aethiops | 5 | ALA4052722 | cell-based format | Scientific Literature | |
9. | ALA4056703 | A | Cytotoxicity against African green monkey CV1 cells assessed as viable cells at 50 uM after 110 hrs by real-time cell analysis relative to control | Chlorocebus aethiops | 3 | ALA4052722 | cell-based format | Scientific Literature | |
10. | ALA4056706 | F | Antiviral activity against Vaccinia virus LIVP harboring GFP infected in African green monkey CV1 cells assessed as virus titer preincubated with cells for 4 hrs followed by viral infection measured after 48 hrs by gentian violet staining-based microscopic analysis | Vaccinia virus | 5 | ALA4052722 | assay format | Scientific Literature | |
11. | ALA4056707 | T | Selectivity index, ratio of CC50 for African green monkey CV1 cells to IC50 for Vaccinia virus LIVP harboring GFP infected in African green monkey CV1 cells | 5 | ALA4052722 | assay format | Scientific Literature | ||
12. | ALA4056708 | F | Induction of IFN-alpha activity in mouse L929 cells infected with Encephalomyocarditis virus at 10 uM preincubated with cells for overnight followed by viral infection by optical microscopic analysis | Mus musculus | 4 | ALA4052722 | cell-based format | Scientific Literature | |
13. | ALA4056709 | F | Induction of IFN-alpha level in BALB/c mouse splenocytes at 10 uM preincubated for 4 hrs measured afte 24 hrs by ELISA | Mus musculus | 5 | ALA4052722 | cell-based format | Scientific Literature | |
14. | ALA4056712 | F | Antiviral activity against Vaccinia virus LIVP harboring GFP infected in African green monkey CV1 cells assessed as inhibition of GFP expression at 30 to 50 uM preincubated for 4 hrs with cells followed by viral infection measured after 24 hrs by flow cytometric analysis relative to control | Vaccinia virus | 4 | ALA4052722 | assay format | Scientific Literature |