#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4015418	U	Cysteamine reactivity of the compound in PBS assessed as second order rate constant for free cysteamine release at 250 uM and pH 7.4 after 90 mins by DTNB reagent based RP-UHPLC analysis		15	ALA4014309	assay format	Scientific Literature
2.	ALA4015424	A	Cytotoxicity against human THP1 cells assessed as reduction in cell viability after 72 hrs by MTT assay	Homo sapiens	16	ALA4014309	cell-based format	Scientific Literature
3.	ALA4015425	A	Cytotoxicity against human THP1 cells assessed as cell viability at 100 uM after 72 hrs by MTT assay	Homo sapiens	9	ALA4014309	cell-based format	Scientific Literature
4.	ALA4015426	B	Inhibition of recombinant human NLRP3 ATPase assessed as hydrolysis of ATP at 100 uM preincubated for 15 mins followed by addition of ATP measured after 40 mins by ADP-Glo assay	Homo sapiens	16	ALA4014309	single protein format	Scientific Literature
5.	ALA4015427	B	Inhibition of recombinant human NLRP3 ATPase assessed as hydrolysis of ATP at 50 uM preincubated for 15 mins followed by addition of ATP measured after 40 mins by ADP-Glo assay	Homo sapiens	16	ALA4014309	single protein format	Scientific Literature
6.	ALA4015428	B	Inhibition of NLRP3 in PMA-differentiated and LPS-primed human THP1 cells assessed as decrease in ATP-induced pyroptosis measured as LDH activity at 10 uM preincubated for 1 hr followed by ATP addition measured after 1 hr by colorimetric assay relative to control	Homo sapiens	13	ALA4014309	assay format	Scientific Literature
7.	ALA4015457	A	Metabolic stability in Sprague-Dawley rat liver microsomes at 100 uM after 2 hrs in presence of NADPH-generating system by UHPLC-MS analysis	Rattus norvegicus	1	ALA4014309	assay format	Scientific Literature
8.	ALA4015485	A	Drug level in Sprague-Dawley rat liver microsomes treated with INF39 at 100 uM up to 2 hrs by UHPLC-MS analysis	Rattus norvegicus	1	ALA4014309	assay format	Scientific Literature
9.	ALA4015486	B	Inhibition of recombinant human NLRP3 ATPase assessed as hydrolysis of ATP preincubated for 15 mins followed by addition of ATP measured after 40 mins by ADP-Glo assay	Homo sapiens	10	ALA4014309	single protein format	Scientific Literature
10.	ALA4015491	A	Drug level in Sprague-Dawley rat ileum tract treated with INF39 at 12.5 mg as suspension in olive oil measured after 2 hrs by UHPLC-M	Rattus norvegicus	1	ALA4014309	assay format	Scientific Literature
11.	ALA4015492	A	Drug level in Sprague-Dawley rat duodenum treated with INF39 at 12.5 mg as suspension in olive oil measured after 2 hrs by UHPLC-M	Rattus norvegicus	1	ALA4014309	tissue-based format	Scientific Literature
12.	ALA4015493	A	Drug level in Sprague-Dawley rat jejunum treated with INF39 at 12.5 mg as suspension in olive oil measured after 2 hrs by UHPLC-M	Rattus norvegicus	1	ALA4014309	tissue-based format	Scientific Literature