# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4038532 | Functional | Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay | Homo sapiens | 8 | ALA4038272 | cell-based format | Scientific Literature | |
2. | ALA4038533 | Functional | Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by CCK-8 assay | Homo sapiens | 8 | ALA4038272 | cell-based format | Scientific Literature | |
3. | ALA4038534 | ADME | Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay | Homo sapiens | 8 | ALA4038272 | cell-based format | Scientific Literature | |
4. | ALA4038535 | Functional | Resistant factor, ratio of IC50 for human Bel7402/5-FU cells to IC50 for human Bel7402 cells | Homo sapiens | 8 | ALA4038272 | assay format | Scientific Literature | |
5. | ALA4038542 | Functional | Cell cycle arrest in human Bel7402/5-FU cells assessed as accumulation at G1 phase at 10 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 52.21%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
6. | ALA4038543 | Functional | Cell cycle arrest in human Bel7402/5-FU cells assessed as accumulation at S phase at 10 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 12.62%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
7. | ALA4038544 | Functional | Cell cycle arrest in human Bel7402/5-FU cells assessed as accumulation at G2 phase at 10 uM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 35.16%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
8. | ALA4038554 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as reduction in cell number at 10 uM after 24 hrs by Hoechst 33342 staining based fluorescent microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
9. | ALA4038555 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as morphological changes at 10 uM after 24 hrs by Hoechst 33342 staining based fluorescent microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
10. | ALA4038556 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as condensed nuclei at 10 uM after 24 hrs by Hoechst 33342 staining based fluorescent microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
11. | ALA4038562 | Functional | Induction of apoptosis in human Bel7402/5-FU cells at 10 uM after 24 hrs by Hoechst 33342 staining based fluorescent microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
12. | ALA4038572 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as live cells at 10 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 91.08%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
13. | ALA4038573 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as early apoptotic cells at 10 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 5.24%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
14. | ALA4038574 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as late apoptotic cells at 10 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 3%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
15. | ALA4038575 | Functional | Induction of apoptosis in human Bel7402/5-FU cells assessed as necrotic cells at 10 uM after 48 hrs by Annexin V-APC/7-AAD staining based flow cytometry (Rvb = 0.58%) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
16. | ALA4038582 | Functional | Induction of microtubule disruption in human Bel7402/5-FU cells at 10 uM after 24 to 48 hrs by DAPI staining based immunofluorescence microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
17. | ALA4038586 | Functional | Reduction in microtubule density in human Bel7402/5-FU cells at 10 uM after 24 to 48 hrs by DAPI staining based immunofluorescence microscopic method | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
18. | ALA4038590 | Functional | Antimigratory activity in human Bel7402/5-FU cells at 10 uM after 24 hrs by wound healing assay | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
19. | ALA4038600 | Functional | Effect on CDK1 expression in human Bel7402/5-FU cells assessed as ratio of CDK1 to beta-actin level at 10 uM after 48 hrs by Western blot analysis (Rvb = 0.33 No_unit) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature | |
20. | ALA4038601 | Functional | Effect on CDK2 expression in human Bel7402/5-FU cells assessed as ratio of CDK2 to beta-actin level at 10 uM after 48 hrs by Western blot analysis (Rvb = 0.43 No_unit) | Homo sapiens | 1 | ALA4038272 | cell-based format | Scientific Literature |