| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4042520 | F | Induction of apoptosis in human A549 cells assessed as reduction in Bcl-2 expression measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4042521 | F | Induction of apoptosis in human A549 cells assessed as increase in Bax expression measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4042522 | F | Induction of apoptosis in human A549 cells assessed as cell shrinkage measured after 72 hrs by Hoechst 33258 staining based fluorescent microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4042523 | F | Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA4042524 | F | Cytotoxicity against mouse LLC cells measured after 72 hrs by MTT assay | Mus musculus | 13 | cell-based format | Scientific Literature | ||
| 6. | ALA4042525 | F | Cytotoxicity against human NCI-H1650 cells measured after 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 7. | ALA4042526 | F | Antiproliferative activity against human A549 cells assessed as reduction in colony formation measured after 7 days by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4042527 | F | Anti-migratory activity against human A549 cells assessed as reduction in cell migration measured after 24 to 72 hrs by wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4042528 | F | Anti-migratory activity against human A549 cells assessed as reduction in cell migration at 5 uM measured after 24 to 72 hrs by wound healing assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4042529 | F | Anti-migratory activity against human A549 cells assessed as reduction in cell migration at 10 uM measured after 24 to 72 hrs by wound healing assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4042530 | F | Anti-migratory activity against human A549 cells assessed as reduction in cell migration at 20 uM measured after 24 to 72 hrs by wound healing assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4042531 | F | Induction of apoptosis in human A549 cells assessed as chromatin condensation measured after 72 hrs by Hoechst 33258 staining based fluorescent microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4042532 | F | Induction of apoptosis in human A549 cells measured after 48 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4042533 | F | Induction of apoptosis in human A549 cells at 5 uM measured after 48 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 5.91 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4042534 | F | Induction of apoptosis in human A549 cells at 10 uM measured after 48 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 5.91 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4042535 | F | Induction of apoptosis in human A549 cells at 20 uM measured after 48 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry (Rvb = 5.91 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4042536 | F | Induction of apoptosis in human A549 cells assessed as increase in cleaved caspase-3 level at 20 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4042537 | B | Inhibition of TNF-alpha induced IkappaBalpha degradation in human A549 cells measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4042538 | B | Inhibition of TNF-alpha stimulated P65 nuclear translocation in human A549 cells at 10 uM pretreated for 2 hrs followed by TNF-alpha induction measured after 20 mins DAPI-staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4042539 | F | Induction of apoptosis in human A549 cells assessed as increase in ROS production at 10 uM by DCFH-DA staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature |
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