# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4014728 | ADME | Inhibition of human CYP1A1 expressed in yeast microsomal membranes at 10 uM using 7-ethoxyresorufin/3-cyano-7-ethoxycoumarin as substrate by fluorescence assay relative to control | Homo sapiens | 20 | ALA4014284 | cell membrane format | Scientific Literature | |
2. | ALA4014729 | Binding | Inhibition of human CYP1B1 expressed in yeast microsomal membranes at 10 uM using 7-ethoxyresorufin as substrate by fluorescence assay relative to control | Homo sapiens | 20 | ALA4014284 | cell membrane format | Scientific Literature | |
3. | ALA4014730 | ADME | Inhibition of human CYP1A2 expressed in yeast microsomal membranes at 10 uM using 7-ethoxyresorufin/3-cyano-7-ethoxycoumarin/7-ethoxy-methyloxy-3-cyanocoumarin as substrate by fluorescence assay relative to control | Homo sapiens | 20 | ALA4014284 | cell membrane format | Scientific Literature | |
4. | ALA4014731 | ADME | Inhibition of human CYP2D6 expressed in yeast microsomal membranes at 10 uM using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate by fluorescence assay relative to control | Homo sapiens | 20 | ALA4014284 | cell membrane format | Scientific Literature | |
5. | ALA4014732 | ADME | Inhibition of human CYP3A4 expressed in yeast microsomal membranes at 10 uM using dibenzylfluorescein as substrate by fluorescence assay relative to control | Homo sapiens | 20 | ALA4014284 | cell membrane format | Scientific Literature | |
6. | ALA4014733 | ADME | Inhibition of human CYP2C9 expressed in yeast microsomal membranes at 10 uM using 3-cyano-7-ethoxycoumarin as substrate by fluorescence assay relative to control | Homo sapiens | 20 | ALA4014284 | cell membrane format | Scientific Literature | |
7. | ALA4014734 | ADME | Inhibition of human CYP2C19 expressed in yeast microsomal membranes at 10 uM using 3-cyano-7-ethoxycoumarin as substrate by fluorescence assay relative to control | Homo sapiens | 20 | ALA4014284 | cell membrane format | Scientific Literature | |
8. | ALA4014742 | ADME | Inhibition of recombinant human liver CYP1A1 expressed in HEK293 cells at 10 uM using 7-ethoxyresorufin as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by EROD assay relative to control | Homo sapiens | 19 | ALA4014284 | cell-based format | Scientific Literature | |
9. | ALA4014743 | Binding | Inhibition of recombinant human liver CYP1B1 expressed in HEK293 cells at 10 uM using 7-ethoxyresorufin as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by EROD assay relative to control | Homo sapiens | 20 | ALA4014284 | cell-based format | Scientific Literature | |
10. | ALA4014744 | ADME | Inhibition of recombinant human CYP1A1 expressed in yeast cells at 10 uM using 7-ethoxyresorufin/3-cyano-7-ethoxycoumarin as substrate by fluorescence assay relative to control | Homo sapiens | 20 | ALA4014284 | cell-based format | Scientific Literature | |
11. | ALA4014745 | Binding | Inhibition of recombinant human CYP1B1 expressed in yeast cells at 10 uM using 7-ethoxyresorufin as substrate by fluorescence assay relative to control | Homo sapiens | 20 | ALA4014284 | cell-based format | Scientific Literature | |
12. | ALA4480899 | Binding | Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/Cyclin D1 (Q4 to I295 residues) expressed in sf9 cells at 10 uM using RBCTF as substrate measured after 1 hr by ADP-glo luminescence assay relative to control | Homo sapiens | 47 | ALA4480390 | cell-based format | Scientific Literature |