| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4017398 | B | Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 2. | ALA4017399 | B | Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA4017400 | B | Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA4017401 | B | Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 5. | ALA4017402 | B | Inhibition of MMP9 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 6. | ALA4017403 | B | Inhibition of recombinant human MMP14 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 7. | ALA4017404 | B | Selectivity ratio of IC50 for recombinant human MMP1 expressed in mouse NSO cells to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4017405 | B | Selectivity ratio of IC50 for recombinant human MMP2 expressed in mouse NSO cells to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4017406 | B | Selectivity ratio of IC50 for MMP8 (unknown origin) to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4017407 | B | Selectivity ratio of IC50 for MMP9 (unknown origin) to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4017408 | B | Selectivity ratio of IC50 for recombinant human MMP14 to IC50 for full length recombinant human MMP13 expressed in mouse NSO cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4017411 | B | Inhibition of MMP13 (unknown origin)-mediated type-2 collagen cleavage assessed as increase in intact collagen at 20 uM after 24 hrs by SDS-PAGE analysis relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 13. | ALA4017412 | B | Inhibition of MMP13 (unknown origin)-mediated type-2 collagen cleavage assessed as increase in intact collagen after 24 hrs by SDS-PAGE analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA4158211 | A | Half life in human liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 46 | microsome format | Scientific Literature | ||
| 15. | ALA4158212 | A | Half life in rat liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 46 | microsome format | Scientific Literature | ||
| 16. | ALA4158213 | A | Half life in mouse liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis | Mus musculus | 46 | microsome format | Scientific Literature | ||
| 17. | ALA4158215 | B | Inhibition of recombinant human full length MMP13 expressed in mouse NS0 cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
| 18. | ALA4158218 | B | Inhibition of recombinant human MMP1 expressed in mouse NS0 cells using Knight substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
| 19. | ALA4158219 | B | Inhibition of recombinant human MMP2 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 45 | single protein format | Scientific Literature | ||
| 20. | ALA4158220 | B | Inhibition of recombinant human MMP8 expressed in mouse NS0 cells using Knight substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 45 | cell-based format | Scientific Literature |
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