# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4046264 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 16:1/16:0 desaturase index after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | ALA4043175 | cell-based format | Scientific Literature | |
2. | ALA4046265 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 18:1/18:0 desaturase index after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | ALA4043175 | cell-based format | Scientific Literature | |
3. | ALA4046266 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as increase in cellular elongase index at 10 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 9 | ALA4043175 | cell-based format | Scientific Literature | |
4. | ALA4046267 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 16:1/16:0 desaturase index at 10 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | ALA4043175 | cell-based format | Scientific Literature | |
5. | ALA4046268 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 18:1/18:0 desaturase index AT 10 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 7 | ALA4043175 | cell-based format | Scientific Literature | |
6. | ALA4046270 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as increase in cellular elongase index at 1 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 1 | ALA4043175 | cell-based format | Scientific Literature | |
7. | ALA4046271 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 16:1/16:0 desaturase index at 1 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 1 | ALA4043175 | cell-based format | Scientific Literature | |
8. | ALA4046272 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in 18:1/18:0 desaturase index at 1 uM after 72 hrs by gas chromatographic analysis | Homo sapiens | 1 | ALA4043175 | cell-based format | Scientific Literature | |
9. | ALA4046274 | Binding | Inhibition of SCD1 in human HepG2 cells assessed as decrease in cellular lipid accumulation at 10 uM after 48 hrs by Oil Red O staining-based assay | Homo sapiens | 2 | ALA4043175 | cell-based format | Scientific Literature | |
10. | ALA4046275 | Binding | Inhibition of recombinant human N-terminal His-tagged JAK2 catalytic domain (826 to 1132 residues) expressed in baculovirus expression system at 10 uM by TR-FRET assay relative to control | Homo sapiens | 1 | ALA4043175 | assay format | Scientific Literature | |
11. | ALA4046276 | Binding | Inhibition of recombinant human N-terminal GST-tagged FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus expression system at 10 uM by TR-FRET assay relative to control | Homo sapiens | 1 | ALA4043175 | assay format | Scientific Literature | |
12. | ALA4046277 | Binding | Inhibition of recombinant human N-terminal GST-tagged FMS cytoplasmic domain (538 to 972 residues) expressed in baculovirus expression system at 10 uM by TR-FRET assay relative to control | Homo sapiens | 1 | ALA4043175 | assay format | Scientific Literature | |
13. | ALA4046278 | Binding | Inhibition of full-length recombinant human N-terminal His-tagged ABL expressed in baculovirus expression system at 10 uM by TR-FRET assay relative to control | Homo sapiens | 1 | ALA4043175 | assay format | Scientific Literature |