# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3992303 | F | Reduction in amphetamine-induced hyperactivity in systemically dosed C57B/6 mouse model of schizophrenia administered at 30 mins after habituation in open field apparatus followed by amphetamine injection measured for 1 hr post dose | Mus musculus | 1 | organism-based format | Patent Bioactivity Data | ||
2. | ALA3992305 | B | Inhibition of asc-1 mediated [3H]-D-serine uptake in P2 fraction of rat forebrain synaptosomes after 4 mins by beta scintillation counting | Rattus norvegicus | 14 | subcellular format | Patent Bioactivity Data | ||
3. | ALA3992306 | B | Inhibition of ASCT2 mediated [3H]-D-serine uptake in rat hippocampal astrocytes | Rattus norvegicus | 14 | cell-based format | Patent Bioactivity Data | ||
4. | ALA3992308 | B | Potentiation of NMDA receptor mediated excitatory post-synaptic currents in the CA1 region of rat hippocampal slices upto 1 hr by whole-cell patch-clamp assay | Rattus norvegicus | 14 | assay format | Patent Bioactivity Data | ||
5. | ALA3992312 | B | Inhibition of human ASCT1 expressed in HEK cells assessed as reduction in [3H]-L-serine uptake after 1 min by beta counting analysis | Homo sapiens | 12 | cell-based format | Patent Bioactivity Data | ||
6. | ALA3992313 | B | Inhibition of human ASCT2 expressed in HEK cells assessed as reduction in [3H]-L-serine uptake after 1 min by beta counting analysis | Homo sapiens | 12 | cell-based format | Patent Bioactivity Data | ||
7. | ALA3992314 | B | Inhibition of ASCT2 mediated [3H]-L-serine uptake in rat hippocampal astrocytes after 5 mins by beta counting analysis | Rattus norvegicus | 9 | cell-based format | Patent Bioactivity Data | ||
8. | ALA3992319 | B | Inhibition of D-serine transporter in Sprague-Dawley rat visual cortex assessed as LTP threshold after 15 mins | Rattus norvegicus | 9 | assay format | Patent Bioactivity Data | ||
9. | ALA3992321 | B | Inhibition of ASCT2 mediated [3H]-D-serine uptake in rat hippocampal astrocytes at 1 mM after 5 mins by beta counting analysis | Rattus norvegicus | 173 | cell-based format | Patent Bioactivity Data | ||
10. | ALA3992322 | B | Inhibition of human ASCT1 expressed in HEK cells assessed as reduction in [3H]-D-serine uptake after 1 min by beta counting analysis | Homo sapiens | 6 | cell-based format | Patent Bioactivity Data | ||
11. | ALA3992323 | B | Inhibition of human ASCT2 expressed in HEK cells assessed as reduction in [3H]-D-serine uptake after 1 min by beta counting analysis | Homo sapiens | 6 | cell-based format | Patent Bioactivity Data | ||
12. | ALA3992325 | F | Reduction in amphetamine-induced hyperactivity in C57B/6 mouse model of schizophrenia at 0.3 mg/kg, ip administered at 30 mins after habituation in open field apparatus followed by amphetamine injection measured for 1 hr post dose | Mus musculus | 1 | organism-based format | Patent Bioactivity Data |