# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4042169 | B | Inhibition of chymotrypsin-like activity of 20S proteasome in human HL60 cells using Suc-LLVYaminoluciferin as substrate after 2 hrs by fluorescence analysis | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
2. | ALA4042170 | F | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
3. | ALA4042171 | F | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
4. | ALA4042172 | F | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA4042173 | F | Antiproliferative activity against human 95-D cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA4042174 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA4042175 | F | Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA4042176 | F | Antiproliferative activity against human Bel7404 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA4042177 | F | Antiproliferative activity against human MKN45 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA4042178 | F | Antiproliferative activity against human SKOV3 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA4042179 | F | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
12. | ALA4042180 | F | Antiproliferative activity against human SW1990 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA4042181 | A | Half life in Sprague-Dawley rat at 3 mg/kg, iv administered as bolus after 24 hrs by LC/MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
14. | ALA4042182 | A | AUClast in Sprague-Dawley rat plasma at 3 mg/kg, iv administered as bolus after 24 hrs by LC/MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
15. | ALA4042183 | A | Volume of distribution in Sprague-Dawley rat plasma at 3 mg/kg, iv administered as bolus after 24 hrs by LC/MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
16. | ALA4042184 | A | Clearance in Sprague-Dawley rat plasma at 3 mg/kg, iv administered as bolus after 24 hrs by LC/MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
17. | ALA4042185 | F | Antitumor activity against human Bel7404 cells xenografted in BALB/c nude mouse assessed as effect on tumor volume at 0.5 mg/kg, iv administered once in two days for 24 consecutive days measured on day 1 of compound dosing relative to control | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
18. | ALA4042186 | F | Antitumor activity against human Bel7404 cells xenografted in BALB/c nude mouse assessed as effect on tumor volume at 1 mg/kg, iv administered once in two days for 24 consecutive days measured on day 1 of compound dosing relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
19. | ALA4042188 | B | Inhibition of trypsin-like activity of 20S proteasome in human HL60 cells using Z-LRRaminoluciferin as substrate after 2 hrs by fluorescence analysis | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
20. | ALA4042189 | B | Inhibition of caspase-like activity of 20S proteasome in human HL60 cells using Z-nLPnLDaminoluciferin as substrate after 2 hrs by fluorescence analysis | Homo sapiens | 15 | cell-based format | Scientific Literature |