# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4051384 | Binding | Displacement of [3H]NMS from human muscarinic acetylcholine receptor M2 expressed in CHOK9 cells after 3 hrs by liquid scintillation counting assay | Homo sapiens | 10 | ALA4049434 | cell-based format | Scientific Literature | |
2. | ALA4051393 | Binding | Binding affinity to human muscarinic acetylcholine receptor M2 expressed in live adherent CHOK9 cells after 2 hrs by liquid scintillation counting assay | Homo sapiens | 3 | ALA4049434 | cell-based format | Scientific Literature | |
3. | ALA4051394 | Binding | Binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cell suspension after 2 hrs by liquid scintillation counting assay | Homo sapiens | 1 | ALA4049434 | assay format | Scientific Literature | |
4. | ALA4051395 | Binding | Binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cell homogenate after 2 hrs by liquid scintillation counting assay | Homo sapiens | 2 | ALA4049434 | assay format | Scientific Literature | |
5. | ALA4051396 | Binding | Binding affinity to human muscarinic acetylcholine receptor M4 expressed in CHOK9 cells after 2 hrs by liquid scintillation counting assay | Homo sapiens | 1 | ALA4049434 | cell-based format | Scientific Literature | |
6. | ALA4051402 | Binding | Binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cells assessed as association rate constant incubated up to 140 mins by liquid scintillation counting assay | Homo sapiens | 3 | ALA4049434 | cell-based format | Scientific Literature | |
7. | ALA4051403 | Binding | Binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cells assessed as dissociation rate constant after 105 mins by liquid scintillation counting assay | Homo sapiens | 3 | ALA4049434 | cell-based format | Scientific Literature | |
8. | ALA4051404 | Binding | Binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cells assessed as dissociation half life after 105 mins by liquid scintillation counting assay | Homo sapiens | 3 | ALA4049434 | cell-based format | Scientific Literature | |
9. | ALA4051405 | Binding | Ratio of binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cells assessed as dissociation rate constant to binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cells assessed as association rate constant | Homo sapiens | 3 | ALA4049434 | cell-based format | Scientific Literature | |
10. | ALA4051407 | Binding | Binding affinity to human muscarinic acetylcholine receptor M2 expressed in live adherent CHOK9 cells assessed as ratio of dissociation rate constant to association rate constant after 2 hrs by liquid scintillation counting assay | Homo sapiens | 2 | ALA4049434 | cell-based format | Scientific Literature | |
11. | ALA4051411 | Physicochemical | Chemical stability of the compound in EtOH/H2O at 0.17 uM at -20 degC after 12 months by HPLC analysis | 1 | ALA4049434 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA4051413 | Binding | Binding affinity to human muscarinic acetylcholine receptor M2 expressed in live adherent CHOK9 cells at Kd in presence of 500-fold excess atropine after 2 hrs by liquid scintillation counting assay relative to control | Homo sapiens | 3 | ALA4049434 | cell-based format | Scientific Literature | |
13. | ALA4051414 | Binding | Binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cell suspension at Kd in presence of 500-fold excess atropine after 2 hrs by liquid scintillation counting assay relative to control | Homo sapiens | 1 | ALA4049434 | assay format | Scientific Literature | |
14. | ALA4051421 | Binding | Competitive binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cell homogenates assessed as W84 pIC50 at 0.4 nM after 2 hrs by liquid scintillation counting assay | Homo sapiens | 1 | ALA4049434 | assay format | Scientific Literature | |
15. | ALA4051422 | Binding | Competitive binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cell homogenates assessed as W84 pIC50 at 1 nM after 2 hrs by liquid scintillation counting assay | Homo sapiens | 1 | ALA4049434 | assay format | Scientific Literature | |
16. | ALA4051423 | Binding | Competitive binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cell homogenates assessed as W84 pIC50 at 2 nM after 2 hrs by liquid scintillation counting assay | Homo sapiens | 1 | ALA4049434 | assay format | Scientific Literature | |
17. | ALA4051424 | Binding | Competitive binding affinity to human muscarinic acetylcholine receptor M2 expressed in CHOK9 cell homogenates assessed as W84 pIC50 at 4 nM after 2 hrs by liquid scintillation counting assay | Homo sapiens | 1 | ALA4049434 | assay format | Scientific Literature |