# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4013133 | B | Antagonist activity at rat alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA4011630 | assay format | Scientific Literature | |
2. | ALA4013134 | B | Antagonist activity at rat alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA4011630 | assay format | Scientific Literature | |
3. | ALA4013135 | B | Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 19 | ALA4011630 | assay format | Scientific Literature | |
4. | ALA4013136 | B | Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 18 | ALA4011630 | assay format | Scientific Literature | |
5. | ALA4013137 | B | Selectivity ratio of IC50 for rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte to IC50 for rat alpha3beta4 nACHR expressed in xenopous laevis oocyte | Rattus norvegicus | 13 | ALA4011630 | assay format | Scientific Literature | |
6. | ALA4013138 | B | Antagonist activity at rat alpha3beta2 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA4011630 | assay format | Scientific Literature | |
7. | ALA4013139 | B | Antagonist activity at mouse alpha1beta1epcilondelta nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Mus musculus | 1 | ALA4011630 | assay format | Scientific Literature | |
8. | ALA4013140 | B | Antagonist activity at rat alpha2beta2 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA4011630 | assay format | Scientific Literature | |
9. | ALA4013141 | B | Antagonist activity at rat alpha2beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA4011630 | assay format | Scientific Literature | |
10. | ALA4013142 | B | Antagonist activity at rat alpha4beta2 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA4011630 | assay format | Scientific Literature | |
11. | ALA4013143 | B | Antagonist activity at rat alpha4beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 1 | ALA4011630 | assay format | Scientific Literature | |
12. | ALA4013144 | B | Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method relative to alpha-conotoxin | Rattus norvegicus | 10 | ALA4011630 | assay format | Scientific Literature | |
13. | ALA4013145 | B | Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method relative to alpha-conotoxin | Rattus norvegicus | 10 | ALA4011630 | assay format | Scientific Literature |