# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3995357 | Binding | Inhibition of full length recombinant human His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 10 | ALA3994596 | assay format | Scientific Literature | |
2. | ALA3995360 | Binding | Inhibition of full length recombinant human His6-tagged PARP2 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 10 | ALA3994596 | assay format | Scientific Literature | |
3. | ALA3995362 | Binding | Inhibition of full length recombinant human His6-tagged PARP3 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 10 | ALA3994596 | assay format | Scientific Literature | |
4. | ALA3995364 | Binding | Inhibition of recombinant human TNKS1 ADP-ribosyltransferase/sterile alpha motif domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 6 | ALA3994596 | assay format | Scientific Literature | |
5. | ALA3995367 | Binding | Inhibition of full length recombinant human His6-tagged PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 10 | ALA3994596 | assay format | Scientific Literature | |
6. | ALA3995370 | Binding | Inhibition of recombinant human His6-tagged PARP14 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 9 | ALA3994596 | assay format | Scientific Literature | |
7. | ALA4303805 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
8. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
9. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
10. | ALA4808149 | Binding | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 | |
11. | ALA4808150 | Binding | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 | |
12. | ALA5138201 | Binding | Inhibition of PARP1 (unknown origin) | Homo sapiens | 4 | ALA5136991 | single protein format | Scientific Literature | |
13. | ALA5138228 | Binding | Inhibition of ROCK1 (unknown origin) | Homo sapiens | 2 | ALA5136991 | single protein format | Scientific Literature | |
14. | ALA5138229 | Binding | Inhibition of ROCK2 (unknown origin) | Homo sapiens | 2 | ALA5136991 | single protein format | Scientific Literature |