#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4418221	Functional	Cytotoxicity in human RPMI8226 cells incubated for 48 hrs by MTT assay	Homo sapiens	29	ALA4417640	cell-based format	Patent Bioactivity Data
2.	ALA4418222	Binding	Inhibition of DEPTOR in human RPMI8226 cells assessed as increase in mTOR kinase activity by measuring induction of p70 phosphorylation at 0.5 uM incubated for 6 hrs by Western blot analysis relative to Perchlorocyclopenta-2,4-dien-1-ylidene)hydrazine	Homo sapiens	29	ALA4417640	cell-based format	Patent Bioactivity Data
3.	ALA4418223	Functional	Cytotoxicity in human MM1S cells incubated for 48 hrs by MTT assay	Homo sapiens	29	ALA4417640	cell-based format	Patent Bioactivity Data
4.	ALA4418224	Binding	Inhibition of DEPTOR in human RPMI8226 cells assessed as increase in mTOR kinase activity by measuring induction of p21 expression at 0.5 to 2 uM uM by Western blot analysis	Homo sapiens	3	ALA4417640	cell-based format	Patent Bioactivity Data
5.	ALA4418227	ADME	Cytotoxicity in human PBL cells incubated for 48 hrs by MTT assay	Homo sapiens	6	ALA4417640	cell-based format	Patent Bioactivity Data
6.	ALA4418228	Toxicity	Therapeutic index, ratio of IC50 for cytotoxicity against human PBL cells incubated for 48 hrs by MTT assay to IC50 for cytotoxicity against human MM1S cells incubated for 48 hrs by MTT assay	Homo sapiens	6	ALA4417640	cell-based format	Patent Bioactivity Data
7.	ALA4418230	Binding	Inhibition of DEPTOR in human RPMI8226 cells assessed as induction of mTORC1 activation at 0.5 uM incubated for 6 hrs co-immunoprecipitation assay	Homo sapiens	4	ALA4417640	cell-based format	Patent Bioactivity Data
8.	ALA4418231	Functional	Cytotoxicity in human MM1S cells at 0.12 to 1 uM incubated for 48 hrs in presence of RAPTOR siRNA by MTT assay	Homo sapiens	2	ALA4417640	cell-based format	Patent Bioactivity Data
9.	ALA4047134	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC1-associated p70 phosphorylation at 0.5 uM after 6 hrs by Western blot analysis relative to NSC126405	Homo sapiens	28	ALA4043223	cell-based format	Scientific Literature
10.	ALA4047135	Functional	Cytotoxicity against human RPMI8226 cells after 48 hrs by MTT assay	Homo sapiens	29	ALA4043223	cell-based format	Scientific Literature
11.	ALA4047136	Functional	Cytotoxicity against human MM1S cells after 48 hrs by MTT assay	Homo sapiens	29	ALA4043223	cell-based format	Scientific Literature
12.	ALA4047137	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC1-associated p70 phosphorylation at 0.25 uM after 6 hrs by Western blot analysis	Homo sapiens	5	ALA4043223	cell-based format	Scientific Literature
13.	ALA4047138	Functional	Induction of apoptosis in human RPMI8226 cells assessed as caspase3 activation at 0.12 to 2 uM after 48 hrs by cytofix/cytoperm staining based flow cytometry	Homo sapiens	6	ALA4043223	cell-based format	Scientific Literature
14.	ALA4047139	ADME	Cytotoxicity against PBL (unknown origin) after 48 hrs by MTT assay	Not specified	6	ALA4043223	cell-based format	Scientific Literature
15.	ALA4047140	Unassigned	Therapeutic index, ratio of IC50 for PBL (unknown origin) to IC50 for human RPMI8226 cells		6	ALA4043223	assay format	Scientific Literature
16.	ALA4047142	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells at 0.5 uM treated 6 hrs followed by DEPTOR immunoprecipitation by immunoblotting analysis	Homo sapiens	4	ALA4043223	cell-based format	Scientific Literature
17.	ALA4047143	Functional	Cytotoxicity against RAPTOR knockdown human RPMI8226 cells at 0.12 to 1 uM after 48 hrs by MTT assay	Homo sapiens	3	ALA4043223	cell-based format	Scientific Literature
18.	ALA4047156	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC1-associated p70 phosphorylation at 1 uM after 6 hrs by Western blot analysis	Homo sapiens	6	ALA4043223	cell-based format	Scientific Literature