# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4000507 | Binding | Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repeat amplification protocol assay | Homo sapiens | 9 | ALA4000158 | single protein format | Scientific Literature | |
2. | ALA4000510 | Physicochemical | Octanol-phosphate buffered saline distribution coefficient, log D of the compound at pH 7.4 measured after 1 min by gamma counting | 4 | ALA4000158 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA4000511 | Physicochemical | Octanol-water partition coefficient, log P of the compound measured after 1 min by gamma counting | 4 | ALA4000158 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4000514 | Physicochemical | Chemical stability of the compound in phosphate buffered saline assessed as compound remaining at 50 MBq measured after 24 hrs by radio-HPLC method | 4 | ALA4000158 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4000515 | ADME | Drug uptake in human MDA-MB-435 cells at 0.2 MBq measured after 24 hrs by gamma counting relative to control | Homo sapiens | 3 | ALA4000158 | cell-based format | Scientific Literature | |
6. | ALA4000526 | Functional | Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell survival at 2 to 16 MBq/ml incubated for 24 hrs measured after 10 days by methylene blue staining based clonogenic assay | Homo sapiens | 2 | ALA4000158 | cell-based format | Scientific Literature | |
7. | ALA4000527 | Functional | Cytotoxicity against human MDA-MB-435 cells assessed as cell survival at 16 MBq/ml incubated for 24 hrs measured after 10 days by methylene blue staining based clonogenic assay | Homo sapiens | 2 | ALA4000158 | cell-based format | Scientific Literature | |
8. | ALA4000530 | Physicochemical | Chemical stability of the compound in phosphate buffered saline assessed as deiodination at 50 MBq measured up to 4 hrs by radio-HPLC method | 1 | ALA4000158 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA4000531 | Physicochemical | Chemical stability of the compound in phosphate buffered saline assessed as decomposition at 50 MBq measured up to 4 hrs by radio-HPLC method | 1 | ALA4000158 | small-molecule physicochemical format | Scientific Literature |