| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4044801 | P | Lipid/water partition coefficient, log P of the compound | 18 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA4044802 | A | Inhibition of COX-1 in rat peritoneal macrophages assessed as reduction in [125I]-6-Keto-PGF1alpha production using arachidonic acid as substrate pretreated for 30 mins followed by substrate addition measured after 30 mins | Rattus norvegicus | 19 | assay format | Scientific Literature | ||
| 3. | ALA4044803 | B | Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreated for 30 mins followed by substrate addition measured after 30 mins | Rattus norvegicus | 19 | assay format | Scientific Literature | ||
| 4. | ALA4044804 | U | Selectivity index, ratio of IC50 for COX1 in rat peritoneal macrophages to IC50 for COX2 in rat peritoneal macrophages | Rattus norvegicus | 19 | assay format | Scientific Literature | ||
| 5. | ALA4044805 | P | Dissociation constant, pKa of the compound | 18 | small-molecule physicochemical format | Scientific Literature |
The page will load shortly, Thanks for your patience!