| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4008790 | B | Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as substrate incubated for 20 mins measured after 1 hr by TR-FRET assay | Homo sapiens | 53 | assay format | Scientific Literature | ||
| 2. | ALA4008794 | B | Inhibition of recombinant human MAOA incubated for 15 mins measured after 30 mins by luminescence-Glo assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA4008795 | B | Inhibition of recombinant human MAOB incubated for 15 mins measured after 30 mins by luminescence-Glo assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA4008796 | B | Inhibition of KDM1B (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA4008797 | B | Inhibition of KDM1A in human THP1 cells assessed as increase in CD14 mRNA expression level at 1 uM after 24 hrs by qRT-PCR analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4008799 | B | Inhibition of KDM1A in human THP1 cells assessed as increase in CD11b mRNA expression level at 1 uM after 24 hrs by qRT-PCR analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4008801 | B | Inhibition of KDM1A in human THP1 cells assessed as increase in CD86 mRNA expression level at 1 uM after 24 hrs by qRT-PCR analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4008803 | B | Inhibition of KDM1A in human THP1 cells assessed as increase in CD86 expression level at 0.5 uM after 48 hrs by flow cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4008804 | B | Inhibition of KDM1A in human THP1 cells assessed as increase in CD11b expression level at 0.5 uM after 48 hrs by flow cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4008805 | F | Antiproliferative activity against human MV4-11 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4008806 | F | Antiproliferative activity against human NB4 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4008807 | F | Antiproliferative activity against human THP1 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4008808 | F | Induction of apoptosis in human THP1 cells at 1 uM after 72 hrs by Annexin V-propidium iodide double staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4008810 | F | Cell cycle arrest in human THP1 cells at 1 uM after 72 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4008812 | F | Anticlonogenic activity against human THP1 cells assessed as inhibition of methylcellulose colony formation at 1 uM after 13 days relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA5127932 | B | Inhibition of recombinant human KDM1A (158 to 852 residues) using H3K4Me2 peptide as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by AlphaLISA assay | Homo sapiens | 2 | single protein format | Scientific Literature |
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