# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4031136 | Binding | Inhibition of C-terminal His-tagged full length Toxoplasma gondii CDPK1 expressed in Escherichia coli BL21 (DE3) using syntide-2 as substrate pre-incubated for 10 mins followed by ATP addition measured after 20 mins by ELISA | Toxoplasma gondii | 28 | ALA4028859 | assay format | Scientific Literature | |
2. | ALA4031137 | Binding | Inhibition of human Src kinase domain (254 to 536 residues) expressed in Escherichia coli BL21 (DE3) using abltide as substrate pre-incubated for 10 mins followed by ATP addition measured after 20 mins by ELISA | Homo sapiens | 28 | ALA4028859 | assay format | Scientific Literature | |
3. | ALA4031138 | Functional | Antiparasitic activity against Toxoplasma gondii RH genotype 1 2F clone expressing bacterial beta-galactosidase infected in human HFF cells preincubated for 4 hrs followed by compound washout measured after 72 hrs by chlorophenol red-beta-D-galactopyranoside based spectrophotometry | Toxoplasma gondii | 28 | ALA4028859 | cell-based format | Scientific Literature | |
4. | ALA4031139 | ADME | Half life in rat liver microsomes at 1 uM by LC-MS/MS analysis | Rattus norvegicus | 28 | ALA4028859 | assay format | Scientific Literature |