# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4028921 | ADME | Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to 20 mins by membrane vesicle transport assay | Homo sapiens | 629 | ALA4028801 | cell-based format | Scientific Literature | |
2. | ALA4028922 | ADME | Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 20 mins by membrane vesicle transport assay | Homo sapiens | 598 | ALA4028801 | cell-based format | Scientific Literature | |
3. | ALA4028923 | ADME | Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 10 mins by membrane vesicle transport assay | Homo sapiens | 629 | ALA4028801 | cell-based format | Scientific Literature | |
4. | ALA4028924 | ADME | Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and GSH measured after 20 mins by membrane vesicle transport assay | Homo sapiens | 629 | ALA4028801 | cell-based format | Scientific Literature | |
5. | ALA4028994 | ADME | AUC in human at 0.35 mg, po QD after 24 hrs | Homo sapiens | 1 | ALA4028801 | organism-based format | Scientific Literature | |
6. | ALA4028995 | ADME | Drug concentration at steady state in human at 0.35 mg, po QD after 24 hrs | Homo sapiens | 1 | ALA4028801 | organism-based format | Scientific Literature | |
7. | ALA4028996 | ADME | Ratio of drug concentration at steady state in human at 0.35 mg, po QD after 24 hrs to IC50 for human BSEP overexpressed in Sf9 insect cells | Homo sapiens | 1 | ALA4028801 | organism-based format | Scientific Literature | |
8. | ALA4029349 | Toxicity | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring severity class index | Homo sapiens | 929 | ALA4028802 | assay format | Scientific Literature | |
9. | ALA4029350 | Toxicity | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring verified drug-induced liver injury concern status | Homo sapiens | 929 | ALA4028802 | assay format | Scientific Literature |