# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4044703 | B | Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells using single stranded poly(U) RNA as substrate after 30 mins by ADP-Glo luminescence assay | Homo sapiens | 30 | ALA4043122 | cell-based format | Scientific Literature | |
2. | ALA4044704 | B | Inhibition of elF4G-induced full length recombinant human N-terminal His6-SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) using single stranded poly(U) RNA as substrate after 30 mins by ADP-Glo luminescence assay | Homo sapiens | 4 | ALA4043122 | assay format | Scientific Literature | |
3. | ALA4044705 | B | Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) using single stranded poly(U) RNA as substrate after 30 mins by ADP-Glo luminescence assay | Homo sapiens | 4 | ALA4043122 | assay format | Scientific Literature | |
4. | ALA4044706 | B | Inhibition of full length recombinant human N-terminal His-FLAG-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 insect cells using single stranded poly(U) RNA as substrate after 30 mins by ADP-Glo luminescence assay | Homo sapiens | 4 | ALA4043122 | cell-based format | Scientific Literature | |
5. | ALA4044707 | P | Solubility of the compound at pH 6.8 | 4 | ALA4043122 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4044708 | B | Inhibition of full length recombinant human N-terminal His-tagged BRR2 helicase activity expressed in baculovirus infected Sf9 cells using 5'-[FITC]-UUCCCCUGCAUAAC-3'/5'-GUUAUGCAGGGGAACCAACGCAUAUCAGUGAGGAUU-3' RNA as substrate after 10 mins in presence of ATP by PAGE analysis | Homo sapiens | 2 | ALA4043122 | cell-based format | Scientific Literature | |
7. | ALA4044710 | P | Permeability of the compound at pH 7.4 by PAMPA | 4 | ALA4043122 | small-molecule physicochemical format | Scientific Literature |