| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4016016 | A | Cytotoxicity against human hTERT-BJ cells assessed as reduction in cell viability after 72 hrs by Resazurin assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4016017 | B | Inhibition of recombinant human dCTPase assessed as increase in melting temperature at 33 uM by SYPRO orange dye based differential scanning fluorimetric analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 3. | ALA4016019 | B | Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite green assay | Homo sapiens | 27 | assay format | Scientific Literature | ||
| 4. | ALA4016021 | B | Inhibition of dCTPase in human HL60 cells assessed as protection against pronase digestion at 10 uM after preincubated for 4 hrs followed by pronase addition for 30 mins by DARTS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4016023 | B | Selectivity ratio of IC50 for MTH1 (unknown origin) to IC50 for recombinant human dCTPase | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 6. | ALA4016024 | B | Selectivity ratio of IC50 for NUDT2 (unknown origin) to IC50 for recombinant human dCTPase | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 7. | ALA4016025 | B | Selectivity ratio of IC50 for NUDT5 (unknown origin) to IC50 for recombinant human dCTPase | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 8. | ALA4016026 | B | Selectivity ratio of IC50 for NUDT9 (unknown origin) to IC50 for recombinant human dCTPase | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 9. | ALA4016027 | B | Selectivity ratio of IC50 for NUDT12 (unknown origin) to IC50 for recombinant human dCTPase | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 10. | ALA4016028 | B | Selectivity ratio of IC50 for NUDT14 (unknown origin) to IC50 for recombinant human dCTPase | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 11. | ALA4016029 | B | Selectivity ratio of IC50 for ITPase (unknown origin) to IC50 for recombinant human dCTPase | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 12. | ALA4016030 | B | Selectivity ratio of IC50 for dUTPase (unknown origin) to IC50 for recombinant human dCTPase | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 13. | ALA4016033 | B | Selectivity ratio of IC50 for NUDT15 (unknown origin) to IC50 for recombinant human dCTPase | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 14. | ALA4016034 | A | Drug uptake in human MCF7 cells up to 20 uM | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4016035 | A | Drug uptake in human HL60 cells at 10 uM | Homo sapiens | 3 | cell-based format | Scientific Literature |
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